UCL Biochemical Engineering's Dr Goldrick, an expert in digital bioprocess engineering, will work with the CGT Catapult to develop a digital twin of the cell expansion phase during CAR-T manufacturing. He will also leverage available Process Analytical Technology (PAT) sensors to enhance understanding of this complex manufacturing process. In this part of the manufacturing process, T-cells previously taken from the patient are stimulated to proliferate and expand. This crucial step in the process is challenging due to the sensitivity and variability of the cells.
Read the full press release at Cell and Gene Therapy Catapult (CGT Catapult)
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