Eastman Dental Institute



The Discoveries Centre for Regenerative and Precision Medicine

UCL researchers have been awarded a prestigious EU Horizon 2020 TEAMING grant, in collaboration with a consortium of Portuguese Universities.

The project will capture and accelerate clinical, innovation and enterprise activities through the foundation of a new Discoveries Centre for Regenerative and Precision Medicine. The Centre will headquarter at the University of Minho in Northern Portugal and there will be a supporting campus at UCL.

Find our more below or visit the Centre's website


UCL researchers have been awarded a prestigious EU Horizon 2020 TEAMING grant, in collaboration with a consortium of Portuguese Universities led by Professor Rui L. Reis at 3B´s Research Group of the University of Minho.

The UCL team is led by Professor Jonathan Knowles, (Division of Biomaterials and Tissue Engineering, Eastman Dental Institute). The other UCL investigators are Dr Ivan Wall (Department of Biochemical Engineering), Professor Giampietro Schiavo (Institute of Neurology), Professor Andreas Schätzlein (School of Pharmacy), Professor Vivek Mudera (Division of Surgery & Interventional Science), Dr Richard Day (Division of Medicine), Professor Tim McHugh (Division of Infection and Immunity) and Dr Jane Kinghorn (Translational Research Office).

The total value of the EU Horizon 2020 grant is €15M, of which UCL have been awarded €5.1M as part of the scheme. Portuguese partners will leverage additional national funding to an impressive total of around €100M over the 7 years of the grant. A key overarching focus for the TEAMING award will be to capture and accelerate clinical, innovation and enterprise activities. The headquarters of the new centre will be at the University of Minho in Northern Portugal and there will be a supporting campus at UCL.


Regenerative and precision medicines are emerging medical research fields that may provide novel treatments for a number of diseases, including musculoskeletal and neurodegenerative disorders, as well as cardiovascular diseases, among others.

These diseases affect millions of people in Europe and worldwide, negatively impact their quality of life and of their family members, and represent a major economic burden on our health care systems. Current therapeutic approaches available for musculoskeletal, neurodegenerative and cardiovascular disorders have proved to be ineffective or insufficient in the long term, which calls for new and innovative strategies to overcome the current challenges presented by these diseases.

The Discoveries Centre’s main goal is to create a new multipolar distributed research Centre of Excellence in the area of Regenerative and Precision Medicine.

The multipolar Centre of Excellence will focus on multidisciplinary research that will be translated into innovative methods and applications for the prevention and treatment of a selected group of disorders: Musculoskeletal, neurodegenerative & Cardiovascular.

The Research & Development performed by the Centre will be grouped into seven different research units:

  • Stem cells biology & Engineering
  • Advanced molecular therapies, Biomarkers, & Advanced Medicinal Products
  • Biomaterials & Tissue engineering approaches
  • Nanomedicine & Drug Delivery
  • Screening, Bioimaging & Advanced Micro-technologies
  • Disease & Tissue Models
  • Systems Medicine

Please see the Discoveries Centre website for more details


As part of the progression of the Centre, we aim to run an exciting series of seminars and other events throughout the year, with a focus on regenerative and precision medicine.

1st Discoveries Forum on Regenerative and Precision Medicine 
25-27 september 2019 (Free event)
Port, Portugal

This Forum will showcase different examples on strategies for the translation of laboratory developments to the clinic with an emphasis on Musculoskeletal, Neurodegenerative and Cardiovascular Disorders. It will join internationally recognized academics and researchers of scientific excellence, industrial participants, experts in scientific dissemination and intellectual property and representatives of regulatory agencies. The scientific program will consist of keynote lectures, oral communications selected from the submitted abstracts, and translational lectures

Find out more


Horizon 2020 Entrepreneurship for Researchers Workshop

24-25 January 2019

The highly interactive one and a half day workshop will cover new ways in which leading Portuguese researchers can successfully develop entrepreneurial mindset and skills.

This event is the second in the series of exploratory events aimed to inform the future needs of the Portuguese partner communities, communicating the Discoveries CTR project.

The overall purpose of the workshop is to provide a taster for the type of support available to help commercialise research and to initiate connections amongst the partners who will eventually form the Discoveries Centre in Portugal.

To book a place on the course, please visit: http://bit.ly/lisbonhorizon2020


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Professor Jonathan Knowles Professor of Biomaterials Science and Head of the Division of Biomaterials and Tissue Engineering j.knowles@ucl.ac.uk 020 3456 1189

Sarah Smerald Research Administrator, Discoveries Centre for Regenerative and Precision Medicine s.smerald@ucl.ac.uk

This project has received funding from the European Union's Horizon 2020 research and innovation programme, under grant agreement No 739572.