Dementia Research Centre


Longitudinal Investigation of FTD

We have studied FTD at the DRC for 30 years and have played a role in some of the major developments of the condition, including helping to define the diagnostic criteria, understanding the neuroimaging features of the condition and developing new clinical, cognitive and fluid biomarkers to help understand the progression of the disease. LIFTD is an ongoing longitudinal study of the sporadic (non-genetic) forms of FTD and involves annual neurological and neuropsychological assessments as well as detailed MRI brain scans. We also ask people to donate samples of blood, urine, and, where possible, spinal fluid. 
The objective of the study is to identify reliable measures of disease onset and progression in people with FTD that can be used in future clinical trials.