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Impact Case studies continued

Millennium Cohort Study: building a picture of a new generation
The Millennium Cohort Study is the benchmark for birth cohort studies globally. It has provided data for influential research on breastfeeding, obesity and immunisation and shaped policy thinking on social mobility, poverty and child development.

Improving the validity of autism spectrum disorder assessment
A test for autistic spectrum disorders, developed at UCL and now included in healthcare guidelines and professional standards around the world, has significantly improved diagnosis of these conditions. It has influenced the activities of healthcare professionals, and helped improve the mental health and welfare of children with suspected autistic disorders.

The Moorfields Regression Analysis improves the management of glaucoma
Neural tissue in the optic nerve head is reduced by glaucoma. UCL researchers developed a diagnostic algorithm for measuring the amount of neural tissue relative to normal. This was incorporated into the Heidelberg Retina Tomograph, a standard imaging device, revolutionising the use of imaging in the clinical management of glaucoma.

Novel brain imaging methods improve neurosurgical treatment for epilepsy
Advances in brain scanning at the UCL Institute of Neurology underpinned major improvements in the surgical treatment of epilepsy, reducing the risk of loss of sight, language or control of limbs. This is now used in epilepsy surgery at the National Hospital for Neurology and Neurosurgery and is being rolled out elsewhere.

Statistical Parametric Mapping
Research at UCL led to the development of a statistical framework and software package for analysing human brain signals measured in brain (e.g., magnetic resonance) imaging scanners. This has catalysed the emergence of a new field of imaging neuroscience, with benefits not only to healthcare practitioners and patients, but also within industry.

Graphical monitoring of clinical outcomes and healthcare quality
A graphical tool for monitoring clinical outcomes developed by UCL researchers has been widely adopted by UK cardiac surgery centres, and has helped a shift in culture towards more open outcome assessment in adult cardiac surgery, which has been credited with reducing mortality rates.