27 September 2013

Charidimou A, Werring DJ. The dilemma of atrial fibrillation in intracerebral haemorrhage: how to balance the risks of ischaemia and bleeding. Eur J Neurol. 2013.


Charidimou A, Jager RH, Fox Z, Peeters A, Vandermeeren Y, Laloux P, et al. Prevalence and mechanisms of cortical superficial siderosis in cerebral amyloid angiopathy. Neurology. 2013; 81(7): 626-32.


Charidimou A, Krishnan A, Werring DJ, Rolf Jäger H.  Cerebral microbleeds: a guide to detection and clinical relevance in different disease settings. Neuroradiology. 2013 Jun;55(6):655-74. doi: 10.1007/s00234-013-1175-4. Epub 2013 May 25.

Summary:  Cerebral microbleeds have emerged as an important new imaging marker of cerebral small vessel disease. With the development of MRI techniques that are exquisitely sensitive to paramagnetic blood products, such as T2*-weighted gradient-recalled echo and susceptibility-weighted sequences, microbleeds have been detected in ever-increasing numbers of patients in stroke and cognitive clinics, as well as in healthy older people and in a variety of other rarer diseases and syndromes. Detection of cerebral microbleeds has clinical implications with respect to the diagnosis of the underlying small vessel disease, the safety of antithrombotic use, and the risk of symptomatic intracerebral haemorrhage, cognitive impairment and dementia.  This article provides a guide to the detection and clinical relevance of cerebral microbleeds in different conditions based on a comprehensive review of the literature and own findings in research and clinical practice.


Charidimou A, Meegahage R, Fox Z, Peeters A, Vandermeeren Y, Laloux P, et al. Enlarged perivascular spaces as a marker of underlying arteriopathy in intracerebral haemorrhage: a multicentre MRI cohort study. J Neurol Neurosurg Psychiatry. 2013; 84(6): 624-9.


Summary: Putting CROMIS-2 into context: Microbleeds as a risk factor for cerebral bleeding - latest evidence from a meta-analysis

Charidimou A, Kakar P, Fox Z, Werring DJ.  Cerebral microbleeds and recurrent stroke risk: systematic review and meta-analysis of prospective ischemic stroke and transient ischemic attack cohorts. Stroke. 2013; 44(4): 995-1001.