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[Research] Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers
15 May 2013
A research team consisting of scientists from the CMMP group, London Centre for Nanotechnology (LCN), National Physical Laboratory, University of Edinburgh, University of Oxford, Freie Universität Berlin and IBM, have now used a combination of nanoscale imaging, computer simulation and de novo protein design to reveal a new mechanism of membrane disruption by antimicrobial peptides.
Antimicrobial peptides are short protein fragments that have been
suggested as future alternatives to current antibiotics. They identify bacteria
and disrupt their membrane structure, thus ultimately killing the bacteria.
[Read more on the LCN's website here or view the publication on the PNAS website here].