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A full list of all our current and completed trials here at the Comprehensive Clinical Trials Unit.
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Antidepressants in Parkinson's Disease. |
Primary Antibiotic prophylaxis using co-trimoxazole to prevent SpontanEous bacterial PeritoniTIs in Cirrhosis. |
Ambroxol to Slow Progression in Parkinson Disease: A phase III multi-centre randomised placebo-controlled trial |
Albumin To prevenT Infection in chronic liveR failurE. |
Safety and Efficacy of Belimumab after B cell Depletion Therapy in Systemic Lupus Erythematosus. |
A phase III prospective, interventional, cohort, superiority study to evaluate the benefit of rapid COVID-19 genomic sequencing (the COVID-19 GENOMICS UK project) on infection control in preventing the spread of the virus in United Kingdom NHS settings. |
Combination therapy for Pulmonary hypertension using RacEcadotril |
International, Bayesian platform adaptive, randomized, placebo-controlled trial assessing the effectiveness of candidate interventions in preventing COVID-19 disease in adults. |
Retinal biomarkers of Alzheimer's disease in Down's syndrome. |
Developmental Optimisation using Lavage in Preterm Haemorrhage in Infants in the UK: A national randomised controlled trial on the efficacy of neuro-endoscopic lavage |
Developing a therapy for Fetal Growth Restriction. |
A randomised, double blind, parallel group, placebo controlled Phase 3 trial of Exenatide once weekly over 2 years as a potential disease modifying treatment for Parkinson's disease. |
A Randomised, Single Masked, Non-Inferiority Trial of Femtosecond Laser Assisted vs Manual Phacoemulsification Cataract Surgery for Adults with Visually Significant Cataract. |
Favipiravir +/- Lopinavir: A RCT of Early antivirals |
Human papillomavirus infection. |
Phase I/II open label, multicentre clinical trial to assess the safety and efficacy of ssAAV-LK03.hAAT.hcoOTC (Gene Therapy) for paediatric patients with ornithine transcarbamylase deficiency. |
A Phase II Clinical Trial to establish Efficacy and Safety of cross-linking in children with Keratoconus. |
Magnetic resonance Enterography (MRE) or ulTRasound In Crohn’s disease Extended Follow-up for predicting disabling disease. |
Minimally invasive autopsy for fetuses and children based on a combination of post-mortem MRI and endoscopic examination: a feasibility study. |
Integrating Care for young people with epilepsy. |
Mycophenolate in limited cutaneous systemic sclerosis |
MRI for early response prediction to anti-TNF therapy. |
MS-STAT2 : Multiple Sclerosis - Simvastatin Trial 2. |
Nicotinamide in Glaucoma (NAMinG) |
OPtimal TIMing of Anticoagulation after Stroke |
First in Human Phase I/II Clinical Trial of RAFT for Aniridia Related Keratopathy. |
A prospective randomised controlled phase II/III non-inferiority clinical trial of rivaroxaban versus warfarin in patients with thrombotic antiphospholipid syndrome, with or without SLE |
Phase 1 safety study of Recombinant Surfactant Protein D to prevent neonatal Chronic Lung Disease (nCLD) in preterm infants. |
A prospective randomised controlled phase II clinical trial of rivaroxaban versus warfarin in stroke patients with antiphospholipid syndrome, with or without SLE. |
Screening programme for pre-eclampsia. |
Total Ankle Replacement vs Arthrodesis. |
A
Antidepressants in Parkinson's Disease. |
Primary Antibiotic prophylaxis using co-trimoxazole to prevent SpontanEous bacterial PeritoniTIs in Cirrhosis. |
Ambroxol to Slow Progression in Parkinson Disease: A phase III multi-centre randomised placebo-controlled trial |
Albumin To prevenT Infection in chronic liveR failurE. |
B
Safety and Efficacy of Belimumab after B cell Depletion Therapy in Systemic Lupus Erythematosus. |
C
A phase III prospective, interventional, cohort, superiority study to evaluate the benefit of rapid COVID-19 genomic sequencing (the COVID-19 GENOMICS UK project) on infection control in preventing the spread of the virus in United Kingdom NHS settings. |
Combination therapy for Pulmonary hypertension using RacEcadotril |
Chloroquine RepurpOsing to healthWorkers for Novel CORONAvirus mitigaTION. |
E
Developing a therapy for Fetal Growth Restriction. |
A randomised, double blind, parallel group, placebo controlled Phase 3 trial of Exenatide once weekly over 2 years as a potential disease modifying treatment for Parkinson's disease. |
G
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K
A Phase II Clinical Trial to establish Efficacy and Safety of cross-linking in children with Keratoconus. |
L
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M
Magnetic resonance Enterography (MRE) or ulTRasound In Crohn’s disease Extended Follow-up for predicting disabling disease. |
Minimally invasive autopsy for fetuses and children based on a combination of post-mortem MRI and endoscopic examination: a feasibility study. |
Integrating Care for young people with epilepsy. |
Mycophenolate in limited cutaneous systemic sclerosis |
MRI for early response prediction to anti-TNF therapy. |
MS-STAT2 : Multiple Sclerosis - Simvastatin Trial 2. |
N
Nicotinamide in Glaucoma (NAMinG) |
O
OPtimal TIMing of Anticoagulation after Stroke |
P
Q
R
First in Human Phase I/II Clinical Trial of RAFT for Aniridia Related Keratopathy. |
A prospective randomised controlled phase II/III non-inferiority clinical trial of rivaroxaban versus warfarin in patients with thrombotic antiphospholipid syndrome, with or without SLE |
Phase 1 safety study of Recombinant Surfactant Protein D to prevent neonatal Chronic Lung Disease (nCLD) in preterm infants. |
A prospective randomised controlled phase II clinical trial of rivaroxaban versus warfarin in stroke patients with antiphospholipid syndrome, with or without SLE. |
S
Screening programme for pre-eclampsia. |
T
Total Ankle Replacement vs Arthrodesis. |
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