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The Comprehensive Clinical Trials Unit at UCL

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Scientific evidence against a nurse accused of deliberately harming patients

19 September 2025, 3:00 pm–5:00 pm

A close up of a baby's hand laying on a bed

While the case of nurse Lucy Letby continues to provoke discussion we might keep in mind that there have been several more such cases. New ones continue to appear.

This event is free.

Event Information

Open to

All

Availability

Yes

Cost

Free

Organiser

Prof Hakim-Moulay Dehbi, PhD – Comprehensive Clinical Trials Unit at UCL

Location

G08
Chadwick Building
Gower Street
London
WC1E 6BT
United Kingdom

These cases are characterized by an absence of witnesses, an absence of material evidence, an absence of plausible motive and no general agreement that a crime has even occurred. The prosecution is based necessarily on scientific evidence. This evidence has two components: the first deals with speculation on how the supposed crimes may have taken place, examples such as insulin poisoning, overfeeding and air embolism being the most common. The second is based on statistics. The statistics, motivated by an unanticipated cluster of adverse events, are believed to show that a crime must have taken place. Furthermore, the statistical correlation between the presence of the accused and the timing of the supposed crimes is such that the most likely culprit is the accused. In this presentation we focus exclusively on the statistical evidence since the other scientific evidence, however interpreted or understood, does not point a finger at anyone in particular. Most of this presentation can be followed by a general audience. Some technical issues are described but without going into deep mathematical detail.


Agenda

15:00 - 15:45: Presentation by Prof John O'Quigley

15:45 - 17:30: Q&A

 

About the Speaker

Prof John O'Quigley

Honorary Professor, UCL at Comprehensive CTU at UCL

Prof O'Quigley is an honorary Professor at UCL, after having worked over several decades as Professor of Mathematics and Statistics at a number of world's leading institutions. His major contributions have been in the field of clinical trials, even though his interests are varied. In this talk, he will rely on three of his recent publications on the questionable use of statistics in Lucy Letby's case and other cases. His recent contributions have generated a lot of debate in the media and beyond - the reason for this will become apparent in the talk