- Annual Conference 2014
- About Us
- Apply to CoMPLEX
- For Students
- Students & Alumni
Modelling: Big Data and Society Conference
A new PhD student publication
Mapping and Measuring Proteomes
Prof. Ruedi Aebersold, Institute of Molecular Systems Biology ETH Zurich and Faculty of Science, University of Zurich, Zurich, Switzerland
Monday 12 July, Location: MRC-LMCB,
The human genome project has taught us that a complete map -in the case of the genome project the complete genomic sequence – along with computational tools to navigate the map - represent invaluable resources for experimental and theoretical biologists. A main consequence of such a complete map is that all the biological processes have to be explainable with the components that constitute the map. Proteomics has not reached the stage that complete maps are available for any species, yet the need for complete, quantitatively accurate and reproducible data sets is becoming increasingly important for systems biology.
In this presentation we will discuss
experimental and computational challenges related to the generation of complete,
reproducible and quantitative proteomic data sets of cell and tissue samples. We
will also discuss the use of selected reaction monitoring for the detection and
quantification of pre determined sets of proteins in biological samples by
selected reaction monitoring.
Ruedi's homepage: http://www.imsb.ethz.ch/researchgroup/rudolfa
1: Lange V, Picotti P, Domon B and Aebersold R ( 2008) Selected reaction monitoring for quantitative proteomics: A tutorial. Molecular Systems Biology 4:222
3: Picotti P, Lam H, Campbell D, Deutsch E, Mirzaei H, Ranish J, Domon B, Aebersold R. (2008) A database of validated assays for the targeted mass spectrometric analysis of the S. cerevisiae proteome Nat Methods; 5(11):913-4.
4: Picotti P, Rinner O, Stallmach R, Dautel F, Farrah T, Domon B, Wenschuh H, Aebersold R (2010) High-throughput generation of selected reaction-monitoring assays for proteins and proteomes. Nat Methods: 7:43-6.
Page last modified on 12 jul 10 11:11