Infection, Immunity and Inflammation Programme
Molecular basis of immunological and inflammatory disease: to apply high-throughput genetics and systematic deep phenotyping of patients to understand the molecular basis of these diseases.
Basic immunological mechanisms: to elucidate these mechanisms through experimentation in informative model systems and study of immunological development and function in children.
Pathogen action: to understand molecular mechanisms of pathogen action through study of microbial genetics and host response to challenge.
Disease prevention: to develop effective methods to enhance disease diagnosis in early childhood and utilise effective vaccination strategies.
Development of a world-leading translational research programme: to undertake clinical trials in children with immunological and inflammatory diseases using novel biologic agents, and cell and gene therapies
Respiratory, critical care & pain: to improve the understanding of early determinants of lung disease and the pathophysiology of children with life-threatening respiratory disease, critically ill children on intensive care and children in pain and to develop novel therapeutic and management strategies to improve their outcome.
- Infection, Inflammation and Rheumatology
- Molecular and Cellular Immunology
- Respiratory, Critical Care and Anaesthesia