Paediatric Neuropathology Group

Our aim is to understand the cellular mechanisms that underlie childhood brain diseases and improve diagnosis for children. We focus on brain tumours and epilepsy.

Biography

I am the Professor of Paediatric Neuropathology at the UCL Great Ormond Street Institute of Child Health and Clinical Lead/Laboratory Director for the department of histopathology at Great Ormond Street Hospital for Children. I run a research programme focussed on paediatric brain tumours and epilepsy. I provide a diagnostic service in paediatric neuropathology. I am Editor in Chief of Neuropathology and Applied Neurobiology and the national lead for the Childhood Solid Tumour domain of the Genomics England Clinical Interpretation Partnership. I was an editor of the WHO classification of childhood tumours (5th edition), and I am a member of the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW). 

Research

The aim of our group is to understand the development of paediatric brain diseases and in particular to improve diagnosis. We focus on brain tumours and epilepsy.

Conditions: Astrocytoma, Brain tumours in children, Focal Cortical Dysplasia, Epilepsy
Neurogenesis,Neuropathology, Progenitors, Stem cells, Temporal lobes
Methods: Cell culture, Confocal microscopy, Gene expression profiling - tissue level, Histology, Immunohistochemistry, light microscopic techniques, Time-lapse imaging, Stereological analysis

UCL Appointments

• Professor of Paediatric Neuropathology
  University College London, Developmental Biology & Cancer Dept

Degrees

• Fellow of the Royal College of Pathologists
  Royal College of Pathologists, UK, 2008

• Member of the Royal College of Pathologists
  Royal College of Pathologists, UK, 2007

• Member of the Royal College of Physicians
  Royal College of Physicians, 2000

• Doctor of Philosophy
  University of Cambridge, 1998

• Bachelor of Medicine, Bachelor of Surgery
  University of Cambridge, 1997

• Master of Arts
  University of Cambridge, 1996

• Bachelor of Arts
  University of Cambridge, 1992

Fields of Research

• Brain
• Brain Tumour
• Cancer
• Epilepsy
• Focal Cortical Dysplasia
• Morphology
• Neural stem cells
• Neuroanatomy

Recent publications

Group members

Miss Stephanie Caixeiro
PhD Student 
stephanie.caixeiro.22@ucl.ac.uk
UCL Profiles page: Stephanie Caixeiro