Childhood Brain Tumours and Epilepsy Research Group

Our aim is to understand the cellular mechanisms that underlie childhood brain diseases and improve diagnosis for children. We focus on brain tumours and epilepsy.

Biography

I am the Professor of Paediatric Neuropathology at the UCL Great Ormond Street Institute of Child Health and Clinical Lead/Laboratory Director for the department of histopathology at Great Ormond Street Hospital for Children. I run a research programme focussed on paediatric brain tumours and epilepsy. I provide a diagnostic service in paediatric neuropathology. I am Editor in Chief of Neuropathology and Applied Neurobiology and the national lead for the Childhood Solid Tumour domain of the Genomics England Clinical Interpretation Partnership. I was an editor of the WHO classification of childhood tumours (5th edition), and I am a member of the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW). 

Research

The aim of our group is to understand the development of paediatric brain diseases and in particular to improve diagnosis. We focus on brain tumours and epilepsy.

Conditions: Astrocytoma, Brain tumours in children, Focal Cortical Dysplasia, Epilepsy
Neurogenesis,Neuropathology, Progenitors, Stem cells, Temporal lobes
Methods: Cell culture, Confocal microscopy, Gene expression profiling - tissue level, Histology, Immunohistochemistry, light microscopic techniques, Time-lapse imaging, Stereological analysis

UCL Appointments

• Professor of Paediatric Neuropathology
  University College London, Developmental Biology & Cancer Dept

Degrees

• Fellow of the Royal College of Pathologists
  Royal College of Pathologists, UK, 2008

• Member of the Royal College of Pathologists
  Royal College of Pathologists, UK, 2007

• Member of the Royal College of Physicians
  Royal College of Physicians, 2000

• Doctor of Philosophy
  University of Cambridge, 1998

• Bachelor of Medicine, Bachelor of Surgery
  University of Cambridge, 1997

• Master of Arts
  University of Cambridge, 1996

• Bachelor of Arts
  University of Cambridge, 1992

Fields of Research

• Brain
• Brain Tumour
• Cancer
• Epilepsy
• Focal Cortical Dysplasia
• Morphology
• Neural stem cells
• Neuroanatomy

Recent publications

Group members

Miss Stephanie Caixeiro
PhD Student 
stephanie.caixeiro.22@ucl.ac.uk
UCL Profiles page: Stephanie Caixeiro