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Prof Tom Jacques
Professor of Paediatric Neuropathology
Developmental Biology & Cancer Dept
UCL GOS Institute of Child Health
- Joined UCL
- 6th Dec 2004
Research summary
The aim of our group is to understand the development of paediatric brain diseases and in particular the roles of neural stem cells in these diseases. We have focussed on brain tumours and epilepsy. Recent highlights include demonstrating how initial mutations cause different types of tumour in the brain and the isolation of a pathological stem cell from a human malformation of cortical development.
Keywords: Brain, Brain Tumour, Cancer, Epilepsy, Focal Cortical Dysplasia, Morphology, Neural stem cells, Neuroanatomy, Neurogenesis,Neuropathology, Progenitors, Stem cells, Temporal lobes
Conditions: Astrocytoma, Brain tumours in children, Focal Cortical Dysplasia, Epilepsy
Methods: Cell culture, Confocal microscopy, Gene expression profiling - tissue level, Histology, Immunohistochemistry, light microscopic techniques, Time-lapse imaging, Stereological analysis
Education
- Royal College of Pathologists, UK
- Doctorate, Fellow of the Royal College of Pathologists | 2008
- Royal College of Pathologists, UK
- Doctorate, Member of the Royal College of Pathologists | 2007
- Royal College of Physicians
- Doctorate, Member of the Royal College of Physicians | 2000
- University of Cambridge
- Doctorate, Doctor of Philosophy | 1998
- University of Cambridge
- Doctorate, Bachelor of Medicine, Bachelor of Surgery | 1997
- University of Cambridge
- Other higher degree, Master of Arts | 1996
- University of Cambridge
- First Degree, Bachelor of Arts | 1992