UCL Great Ormond Street Institute of Child Health


Great Ormond Street Institute of Child Health

Prof Alastair Sutcliffe

Prof Alastair Sutcliffe

Professor of General Paediatrics

ICH Pop, Policy & Practice Prog

UCL GOS Institute of Child Health

Joined UCL
1st Jan 1997

Research summary

I have conducted studies in outcomes of early life since 1993, these include the first on outcome of embryo cryopreservation, PGD and twin twin transfusion syndrome.These studies continue, with the first on Oocyte cryopreservation outcome, and PCOS outcome studies.

I have conducted two cancer epidemiology studies, one to estimate the risk of cancer in women treated with ART (Assisted Reproductive Therapies) and also separately child cancer risk.

I recently completed a major and innovative a study investigating health in children born to older Mothers.

I was chief investigator in a randomized controlled trial to determine the effect of frenotomy on tongue tied breast fed infants.

I am chief investigator on a study which will establish a secure means of identifying acholuric stools.

With Belgian collaborators we  investigated epigentic risk in ART conceived UK teenagers.

I am also a member of the STOP consortium http://www.stop-study.com/ whose brief is to assess suicidality risk in children exposed to certain medicines such as SSRI's and Montelukast.

I lead to Bench two Bedside projects, the first is in collaboration with Dr Alastair Baker and Professor Long Lin. It aims to develop a screening tool to allow early recognition of Biliary Atresia and other obstructive liver diseases of neonatal life.

The second is in its early stages but aims to develop a preventive treatment for premature labour caused by infection. This is in collaborations with Professors Paul Long, Catherine Tuleu and Dr Paul Hardiman.

I have  a major role in medicines for children and am conducting research involving pharmacovigilance. I am presently a member of the WEB-RADR consortium led by the MHRA and funded by the EU which will improve Pharmacy vigilance reporting across the EU via an IMI grant.

I am leading a study using National Pupil Database data to investigate the educational prospects of children treated for cancer in childhood

A summary of my research efforts around Assisted reproductive therapies was given in an interview with Chris Jones from the Faculty of Health and Social Care at Edge Hill University, which can be viewed at http://www.eshare.edgehill.ac.uk/4971/1/index.html

My present reseach in ART outcomes is funded by the medical Research Council until 2019.

Teaching summary

Commended Teacher UCLH 2009-10

Excellence in Medical Education Awards 2008

Top Teacher 2007-8





London School of Hygiene and Tropical Medicine
PG Dip CT, Paediatrics and Child Health | 2008
Vrije Universiteit Brussel
PhD, Medical Sciences | 2008
University of London
MD, Medical Science | 2000
Royal College of Paediatrics and Child Health
FRCPCH, Paediatrics and Child Health | 1997
Royal College of Physicians
FRCP, Clinical Medicine | 1992
University of Manchester
MB.ChB, Medical Microbiology | 1987


Professor  Sutcliffe is an internationally known expert on IVF children and has led studies in this field since 1993. A Professor of General Paediatrics he is on the BPSU scientific board, he is also an accomplished community paediatrician and is present assistant convenor to BACCH.

He is chief medical advisor to Make-a-Wish Foundation UK. he is a member of the RCPCH academic board and founder of the research network www.gapruki.org.uk.

This latter organisation intends to investigate common disorders in IPD,OPD and community settings and  generate evidence for better practise.

He is also a general, developmental and adolescent pediatrician working clinically at UCLH and is also an honorary consultant at  GOSH and the Whittington Hospitals.