UCL Great Ormond Street Institute of Child Health


Great Ormond Street Institute of Child Health

Prof John Achermann

Prof John Achermann

Professor of Paediatric Endocrinology

ICH Genetics & Genomic Medicine Prog

UCL GOS Institute of Child Health

Joined UCL
1st Apr 2001

Research summary

Our main research interests include the molecular genetics of adrenal and reproductive development and function, and their relevance to human disease or disease susceptibility. Our current research focuses on the role of steroidogenic factor-1 (SF-1) in endocrine development and function, as well as the molecular basis of variant or novel phenotypes associated with endocrine conditions and their implications for patient care. We are currently investigating novel mechanisms of adrenal and reproductive biology in humans as part of a Wellcome Trust Senior Fellowship and novel genetic aspects of testis development as part of the European Union (FP7) Consortium, EuroDSD.

Teaching summary

Steering Committee, ESPE Science School;

Annual Meeting Steering Committee, The Endocrine Society (2006-10);

Steering Committee, ESPE Summer School (2005-09).


University of Cambridge
PhD, Medical Sciences | 2011
Royal College of Physicians
FRCP, Paediatrics | 2009
Royal College of Paediatrics and Child Health
FEL, Paediatrics and Child Health | 2008
University of Cambridge
MD, Medicine | 1998
Royal College of Physicians
MRCPCH, Paediatrics | 1996
Royal College of Physicians
MRCP, Paediatrics | 1994
Royal College of Physicians
DCH, Child Health | 1993
University of Cambridge
MA, | 1992
University of Cambridge
MB.ChB, Medicine/Surgery | 1990
University of Cambridge
BA Hons, Zoology | 1988


I trained in Medicine in Cambridge (1991) and Pediatric Endocrinology in London (MD 1997) before undertaking a post-doctoral fellowship in Molecular Medicine at Northwestern University, Chicago, USA (1998-2001). I completed my clinical training with a Clinician Scientist award from The Wellcome Trust and since 2006 have been a Wellcome Trust Senior Fellow at UCL Institute of Child Health and an Honorary Consultant in Paediatric Endocrinology at Great Ormond Street Hospital. My research interests include adrenal and sex development, genetic mechanisms of disease and nuclear receptor biology.