UCL Great Ormond Street Institute of Child Health


Great Ormond Street Institute of Child Health

Prof Mehul Dattani

Prof Mehul Dattani

Professor of Paediatric Endocrinology

ICH Genetics & Genomic Medicine Prog

UCL GOS Institute of Child Health

Joined UCL
1st Mar 1991

Research summary

My group is currently investigating the genetic basis of pituitary and forebrain development, particularly in relation to the aetiology of disorders of forebrain and pituitary development. We have established the genetic basis of hypopituitarism in a significant number of patients presenting to the Paediatric Endocrinology clinics. We were the first to describe a genetic basis for a disorder called septo-optic dysplasia (SOD) which consists of forebrain, pituitary and eye defects. We have established collaborations with a number of national and international clinical and non-clinical scientists. As a result of these collaborations we have established a large collection of DNA samples from patients with various forms of hypopituitarism.

Teaching summary

I supervise a number of PhD students and post-doctoral fellows. Additionally I supervise a number of Specialist Registrars in training and clinical fellows.


Middlesex Hospital Medical School
DCH, Paediatrics | 1987
Middlesex Hospital Medical School
MBBS, Medicine/Surgery | 1984