UCL Great Ormond Street Institute of Child Health


Great Ormond Street Institute of Child Health

Dr Pat Tookey

Dr Pat Tookey

Honorary Associate Professor

Population, Policy & Practice Dept

UCL GOS Institute of Child Health

Joined UCL
1st Mar 2003

Research summary

Pat Tookey's research focused mainly on the prevention and management of infections affecting pregnant women and their children, including HIV, syphilis, herpes, rubella and cytomegalovirus. She was responsible (1995-2015) for the National Study of HIV in Pregnancy and Childhood (NSHPC) through which the diagnosis, management and outcome of HIV in pregnancy is monitored, as well as mother-to-child transmission of HIV, and the impact of pre-natal and perinatal exposure to HIV infection and antiretroviral drugs on infected and uninfected children . She collaborated closely with colleagues at the MRC Clinical Trials Unit on the Collaborative HIV Paediatric Study (CHIPS), and the AALPHI (Adolescents and Adults with Perinatally Acquired HIV Infection) Study, to explore the long term outcomes of perinatally acquired HIV. Pat worked closely with clinicians in CHIVA (the Children’s HIV Association of the UK and Ireland), and was involved in national and European HIV collaborations.  She also ran the UK’s long-standing National Congenital Rubella Surveillance Programme, maintained a research interest in CMV, and was involved in the review and development of antenatal infection screening programmes.

Teaching summary

Pat is an experienced lecturer and teacher. She was responsible for the Epidemiology Module on the MSc in Paediatrics and Child Health based at UCL Institute of Child Health until her retirement. She also contributed to the Immunisation and Infectious Diseases Module of the MSc. Externally she taught on many CPD accredited courses and workshops on infections and screening.


Pat studied English at Royal Holloway College, London University and worked in publishing for several years. In 1981 she joined the Department of Community Medicine at Charing Cross Hospital Medical School as a research assistant, working on a major prospective study of cytomegalovirus (CMV) infection in pregnancy. Moving to the Institute of Child Health in 1986, Pat continued to work on CMV, as well as extending her interests to other infections affecting pregnant women and children.  She studied for a Masters in Epidemiology at the London School of Hygiene and Tropical Medicine in 1989/90, and completed her PhD, which explored the risks and consequences of cytomegalovirus infection in pregnancy, in 2000. She managed the National Study of HIV in Pregnancy and Childhood, a comprehensive surveillance study of HIV in pregnant women and their children in the UK and Ireland, between 1995 and 2015, along with several associated research studies. Pat formally retired from her full-time post at ICH at the end of 2015. She has an honorary contract (Associate Professor) with the Population, Policy and Practice Research and Teaching Department.