UCL Great Ormond Street Institute of Child Health


Great Ormond Street Institute of Child Health

Prof Owen Williams

Prof Owen Williams

Professor of Cancer Biology

Developmental Biology & Cancer Dept

UCL GOS Institute of Child Health

Joined UCL
1st Apr 2002

Research summary

Haematopoiesis and Leukaemia Group


Group Members


Luca Gasparoli (Post Doctoral Fellow)

Clemence Virely (Post Doctoral Fellow)

Katherine Clesham (Clinical PhD Student)

Mechanisms of oncogenesis in infant and childhood leukaemia 

Chromosomal translocations are frequent in infant and childhood leukaemia. These translocations often result in the generation of unique fusion genes. We investigate the function of fusion genes that are commonly associated with infant and childhood acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML), using molecular and cellular modelling approaches. The goal of this research is to develop novel therapeutic approaches for leukaemias that are difficult to treat with conventional chemotherapy.


University College London
Doctorate, Doctor of Philosophy | 1991
University College London
First Degree, Bachelor of Science (Honours) | 1987