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Image-guided Surgery for Children’s Cancers

Principal Investigator, Mr Stefano Giuliani

Research

Mr Giuliani and his team are working to develop image-guided surgery for Neuroblastoma and other paediatric solid tumours. His research vision is to help surgeons better visualise cancer at the time of the resection. His team is developing a novel platform to enhance surgical precision to eradicate children cancers with fluorescence, photoacoustic imaging, and other innovative technologies. These techniques will help reduce damages to normal organs and obtain a complete removal of the tumour, leading to better surgical and oncologic outcomes.

Mr Giuliani’s group is linked with engineers, physicists, biologists, and other clinicians at UCL and at the Institute of Cancer Research-UK to translate laboratory-based findings to the children quickly and effectively.

Biography

Mr Giuliani is a Consultant Specialist Neonatal and Paediatric Surgeon at Great Ormond Street Hospital for Children in London. He holds an honorary Associate Professorship at the Great Ormond Street Institute of Child Health at UCL.

Briefly, he obtained his medical degree at the University of Udine (Italy) in 2000. He completed his specialist training in Paediatric Surgery at the University of Padova (Italy) in 2006. Then he worked for four years, clinically and as a PhD student, at the Children’s Hospital Los Angeles and the University of Southern California. He completed his PhD in Developmental Medicine and Health Planning Science at the University of Padova (Italy) in 2010. After that, he worked as a Consultant Paediatric Surgeon and honorary Senior Lecturer at St George’s University Hospitals (2011-2016). In 2015, he completed the Global Clinical Scholars Research Training Program (GCSRTP) at Harvard Medical School. This was a blended learning program in epidemiology and research with a focus on clinical trials.

Mr Giuliani moved to Great Ormond Street Hospital and the Institute of Child Health (ICH) at UCL in January 2017; since then, he has been focusing his clinical and academic career on paediatric surgical oncology. Mr Giuliani is a Co-Investigator at the Wellcome EPSRC Centre for Interventional and Surgical Sciences (WEISS) at UCL, where he regularly supervises clinical fellows and PhD students.

In 2019, he was awarded the Clinical Academic Research Partnership (CARP) from the Medical Research Council with the project titled ‘Colour-coded surgery in neuroblastoma: developing a dual PET and Near-Infrared Fluorescent Imaging (NIRF) probe to accurately visualise tumour from diagnosis to resection’.

In 2021, he was awarded the Wellcome Trust – Innovator Award together with a multidisciplinary team of basic scientists and biomedical engineers with a project titled ‘Novel image-guided therapeutics to improve surgical precision and loco-regional control in Neuroblastoma’.

Mr Giuliani has published more than 90 peer-reviewed papers and ten book chapters.

Teaching

Lead for Medical Students and Medical doctors visitors in the Department of Specialist Neonatal and Paediatric Surgery, Great Ormond Street Hospital.

Educational and Clinical Supervisor for Junior Doctors and Specialist Registrars in the Department of Specialist Neonatal and Paediatric Surgery, Great Ormond Street Hospital.

Group Members

Dr Laura Privitera
Research Fellow
l.privitera@ucl.ac.uk
UCL Profiles page: Laura Privitera

Mr Jonathan Neville 
PhD Student
j.neville@ucl.ac.uk

Funders, Collaborators and Partners

The Institute of Cancer Research Logo

wellcome EPSRC centre logo
wellcome Logo
Wellcome Trust

Image for GOSH Children's CHarity

NIHR Children and Families Policy Research Unit logo
OHCF Logo
 
Publications

Active publication list available on Mr Giuliani's UCL Profiles page