The Future

The lecture will be streamed via our YouTube Cannel.

The lectures will be delivered by:

Dr Julien Baruteau

MRC Clinician Scientist, Genetics and Genomic Medicine Research and Teaching Department, UCL Great Ormond Street Institute of Child Health (ICH)

Title: "When little paws take big steps"

Dr Julien Baruteau is a MRC Clinician Scientist Fellow at ICH and a Honorary Consultant in Metabolic Medicine at Great Ormond Street Hospital for Children. He received his medical graduation in Toulouse and specialised in the field of inherited metabolic diseases in Paris before joining Great Ormond Street Hospital for Children in 2012. He developed gene therapy for an orphan disease in Professor Simon Waddington’s group at University College London and he was awarded a PhD in Gene Therapy in 2017. He then joined Professor Paul Gissen’s group at Great Ormond Street Institute of Child Health working on translating gene therapy for paediatric patients. In 2020, he was awarded a MRC Clinician Scientist Fellowship to explore cerebral arginine metabolism. His research group focuses on developing novel therapies for inherited metabolic diseases, mainly urea cycle defects.

Dr Alice Giustacchini

Non Clinical Lecturer in CAR T-cell Therapy, Infection, Immunity and Inflammation Research and Teaching Department, UCL Great Ormond Street Institute of Child Health (ICH)

Title: “Fighting cancer one cell at a time”

Alice Giustacchini obtained her PhD from San Raffaele University in Milan under the supervision of Professor Luigi Naldini, with a project focusing on the role of microRNAs in the regulation of haematopoietic stem cell functions. She next moved to the UK to undertake a post-doc in the laboratories of Professors Adam Mead and Sten Eirik Jacobsen, at the University of Oxford. During her post-doc, she focused on the development of novel single-cell approaches to resolve the impact of cell heterogeneity on leukaemia therapy response. In 2019 she joined UCL Great Ormond Street Institute of Child Health (GOS ICH) as a group leader and Lecturer in CAR T cells.  Alice's group research at GOS ICH revolves around normal and malignant haematopoiesis, with a strong focus on stem cell biology, single-cell technologies and T cell-based immunotherapies. Her group aims to understand what makes leukaemia unresponsive to conventional therapies and they combine single-cell multi-omics with immunologic and stem cell functional assays to develop precision immunotherapy strategies.

The lectures will be followed by a Q&A session via slido.com. Event code: #ICH75FUTURE

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For any queries, please contact ICH Communication Office at ich.comms@ucl.ac.uk.