Professor Charles M. Marson

  Charles Marson is Professor of Organic Chemistry. Currently, his research group includes 5 PhD students and a Masters student. His areas of research include organic synthesis, especially the development of stereocontrolled reactions, cascade processes and asymmetric synthesis. Another major research theme is and the design and synthesis of enzyme inhibitors. Charles Marson received his B.A. and M.A. degrees in Natural Sciences from the University of Cambridge, and PhD and DSc degrees from the University of East Anglia. His PhD research under the direction of Professor A. R. Katritzky, FRS on the synthesis of polycyclic heterocycles afforded the synthesis of the first bispyrylium macrocycle of twelve fused rings. After postdoctoral research he was appointed to Lectureships at the University of Sheffield and Queen Mary College, University of London before appointments at UCL as a Reader, and in 2004 as Professor or Organic Chemistry. 
Summary of research group
  Research in the Marson group involves the discovery of new synthetic organic methodology and the targeted synthesis of organic compounds for use in medicinal chemistry and chemical biology. An illustrated research summary can be found here: charles-marson-research.pdf. Research themes include: development of stereocontrolled tandem processes, especially polysubstituted scaffolds for use in medicinal chemistry; catalytic asymmetric synthesis; design and synthesis of anti-cancer compounds including enzyme inhibitors; asymmetric synthesis of enantiopure C2-symmetric compounds including organofluorine compounds; synthesis of saturated N-heterocyclic systems with stereocontrol.
Research highlights
  Research themes include the design and synthesis of anti-cancer agents and enzyme inhibitors, the synthesis of fused and bridged scaffolds for medicinal chemistry, catalytic asymmetric synthesis, and the development of tandem and stereocontrolled processes in organic chemistry. An illustrated summary of research themes can be found here: charles-marson-research.pdf.
Research Facilities
  • NMR spectroscopy
  • Mass spectrometry
  • IR and
  • UV spectroscopy
  • HPLC
  • CChem FRSC. Member
  • American Chemical Society
Research interests
  • Synthetic methodology: tandem and stereocontrolled processes
  • Catalytic asymmetric synthesis
  • Synthesis of fused and bridged scaffolds for medicinal chemistry
  • Medicinal chemistry: synthesis of anti-cancer agents and enzyme inhibitors
  • CHEM1201 – Basic Organic Chemistry
  • CHEM3004 – Chemistry Literature Project
  • CHEM3204 – Principles of Drug Design
  • CHEMM201 – Stereochemical Control in Asymmetric Total Synthesis