Dr Jonathan Wilden

  Jon Wilden is senior lecturer in organic chemistry. His group currently consists of one postdoc, two PhD students, one MRes student and two MSci final-year undergraduate students. Currently, work in the Wilden group is focused around two main themes (1) new radical methodology including development and mechanistic aspects of transition metal free reactions, and (2) the development of novel peptidomimetics and biologically active molecules. He has worked at UCL since 2003 (2003-5: PDRA; 2005-14: Lecturer; 2014-present: Senior Lecturer). Before this, he was a postdoctoral research associate at the University of Sussex, working with Professor Stephen Caddick. He obtained his PhD from the University of Southampton under the direction of Professor David Harrowven.  
Summary of research group
  Currently, research in the Wilden group is focused on new radical methodology and transition metal free reactions and has been supported by EPSRC, Wellcome Trust, Leverhulme Trust and GSK. The group also has interests in the development of new reactions and the application of these reactions to the preparation of biologically relevant molecules. We have been particularly interested in the development of peptide mimetics based around the sulfonamide group and have also exploited this motif as a tool for unusual synthetic transformations.
Research highlights
Research Facilities
  • Mass Spectrometry
  • NMR Spectroscopy
  • EPR Spectroscopy
Research interests
  • Transition metal-free processes
  • Sustainable chemistry
  • Synthesis of biologically active molecules
  • Radical reactions
  • Organic reaction mechanisms
  • Peptidomimetics
  • Electron transfer reactions
  Lecturer: 1st year core organic chemistry and 3rd year core organic chemistry. Director of the PhD and MRes programmes in organic chemistry & drug discovery.