Professor Charles M. Marson

Summary

Charles Marson is Professor of Organic Chemistry. Currently, his research group includes 5 PhD students and a Masters student. His areas of research include organic synthesis, especially the development of stereocontrolled reactions, cascade processes and asymmetric synthesis. Another major research theme is and the design and synthesis of enzyme inhibitors. Charles Marson received his B.A. and M.A. degrees in Natural Sciences from the University of Cambridge, and PhD and DSc degrees from the University of East Anglia. His PhD research under the direction of Professor A. R. Katritzky, FRS on the synthesis of polycyclic heterocycles afforded the synthesis of the first bispyrylium macrocycle of twelve fused rings. After postdoctoral research he was appointed to Lectureships at the University of Sheffield and Queen Mary College, University of London before appointments at UCL as a Reader, and in 2004 as Professor or Organic Chemistry.

Summary of research group

Research in the Marson group involves the discovery of new synthetic organic methodology and the targeted synthesis of organic compounds for use in medicinal chemistry and chemical biology. An illustrated research summary can be found here: charles-marson-research.pdf. Research themes include: development of stereocontrolled tandem processes, especially polysubstituted scaffolds for use in medicinal chemistry; catalytic asymmetric synthesis; design and synthesis of anti-cancer compounds including enzyme inhibitors; asymmetric synthesis of enantiopure C2-symmetric compounds including organofluorine compounds; synthesis of saturated N-heterocyclic systems with stereocontrol.

Research highlights
	Research themes include the design and synthesis of anti-cancer agents and enzyme inhibitors, the synthesis of fused and bridged scaffolds for medicinal chemistry, catalytic asymmetric synthesis, and the development of tandem and stereocontrolled processes in organic chemistry. An illustrated summary of research themes can be found here: charles-marson-research.pdf.

Research Facilities
	NMR spectroscopy Mass spectrometry IR and UV spectroscopy HPLC

Awards

Memberships
	CChem FRSC. Member American Chemical Society

Research interests
	Synthetic methodology: tandem and stereocontrolled processes Catalytic asymmetric synthesis Synthesis of fused and bridged scaffolds for medicinal chemistry Medicinal chemistry: synthesis of anti-cancer agents and enzyme inhibitors

Teaching
	CHEM1201 – Basic Organic Chemistry CHEM3004 – Chemistry Literature Project CHEM3204 – Principles of Drug Design CHEMM201 – Stereochemical Control in Asymmetric Total Synthesis

Professor Charles M. Marson

All publications

Recent publications