It’s all about the particles – Biomedical and Materials Applications of Nanosystems

3 March 2017

by Professor Vincent Rotello

Tuesday 28th March 2017

11:15am ILDH (U3 – Andy Burroughs Seminar Room), Royal Free Hospital 


3:00pm Chemistry Auditorium, UCL 

This talk will focus on the use of nanoparticles as therapeutics and diagnostics. We will discuss highly efficient nanoparticle-based vehicles that deliver siRNA and proteins directly to the cytosol, completely circumventing endosomal mechanisms.  Applications of these delivery strategies to immunomodulation and gene editing will be presented. Finally, this presentation will also feature the use of nanoparticles for diagnostic applications, focusing on using selective nanoparticle-protein interactions to generate array-based ("chemical nose") sensors for detection of cancer and high throughput screening of therapeutic agents.

Vincent Rotello is the Charles A. Goessmann Professor of Chemistry and a University Distinguished Professor at the University of Massachusetts at Amherst. He received his B.S. in Chemistry in 1985 from Illinois Institute of Technology, and his Ph. D. in 1990 in Chemistry from Yale University. He was an NSF postdoctoral fellow at Massachusetts Institute of Technology from 1990-1993, and joined the faculty at the University of Massachusetts in 1993. He has been the recipient of the NSF CAREER and Cottrell Scholar awards, as well as the Camille Dreyfus Teacher-Scholar, the Sloan Fellowships. He was recognized in 2014 and 2015 by Thomson Reuters as one of the "Most Influential Scientific Minds", and in 2016 he was awarded the Bioorganic Chemistry award by the Royal Society of Chemistry.

Professor Rotello will be presenting a short seminar at 11.15 am in the Andy Burroughs Seminar Room (Upper 3rd – ILDH), and a full seminar in the Dept. of Chemistry (CIB – Chemistry Auditorium) at 3 pm. If you would like to meet with Professor Rotello at any point in the day then please email w.peveler@ucl.ac.uk to arrange.