We take an active approach to research and are interested in developing the best results to assess and manage glycogen storage diseases.
To test if Sodium Valproate can improve symptoms of people with McArdle disease during exercise
Muscular Dystrophy UK
London and Copenhagen
15 required (active)
Study aims: Early diagnosis, high quality advice and management, and to identify suitable candidates for inclusion in future studies of treatments and trials of drugs.
Euromac is a registry of people diagnosed glycogen storage diseases.
The registry is a secure, anonymised and confidential
database designed to contain the medical data related to people who give their consent to inclusion.
EUROMAC aims to promote awareness and understanding of the conditions, improve standards of diagnosis and care and to promote research.
By being included in the registry, patients
will be contributing to the well-being of future generations
of people with these conditions.
Further information about this study can be obtained from the MRC Centre Clinical Trials Coordinator on 020 3448 8011.
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Buckley JP; Quinlivan RM; Sim J; Eston RG; Short DS. Heart rate and perceived muscle pain responses to a functional walking test in McArdle disease. Journal of Sports Sciences. 32(16):1561-9, 2014
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Howell JM; Walker KR; Creed KE; Dunton E; Davies L; Quinlivan R; Karpati G. Phosphorylase re-expression, increase in the force of contraction and decreased fatigue following notexin-induced muscle damage and regeneration in the ovine model of McArdle disease. Neuromuscular Disorders. 24(2):167-77, 2014 Feb.
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Muniz-Pumares D, Pedlar C, Godfrey R, Glaister M. A comparison of methods to estimate anaerobic capacity: Accumulated oxygen deficit and W' during constant and all-out work-rate profiles. J Sports Sci. 2017 Dec;35(23):2357-2364
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Scalco RS; Gardiner AR; Pitceathly RD; Zanoteli E; Becker J; Holton JL; Houlden H; Jungbluth H; Quinlivan R. Rhabdomyolysis: a genetic perspective. Orphanet Journal Of Rare Diseases. 10(1):51, 2015.
Scalco RS, Lorenzoni PJ, Lynch DS, Martins WA, Jungbluth H, Quinlivan R, Becker J. Polymyositis without beneficial response to steroid therapy: Should Miyoshi Myopathy be a differential diagnosis? Am J Case Rep. 2017 Jan 5;18:17-21.
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