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CLEO Systems: Building Agility through Infrastructure Development

CLEO Systems made significant technical advancements with support from the CDI Impact Accelerator programme, enhancing their electronic prescribing app, CLEO SOLO EPS.

CLEO Systems

13 December 2024

CLEO Systems is dedicated to delivering intuitive solutions that empower clinicians to improve patient experience and enhance efficiency across the healthcare ecosystem. Through their participation in the CDI programme, CLEO Systems sought to establish the technical infrastructure needed to scale their SOLO EPS system, which has seen high demand from NHS Trusts in the UK. With ambitions for international expansion, CLEO aimed to build agility by strengthening their infrastructure to support both current demands and future growth.

The Challenge: Infrastructure Limitations Preventing Expansion of CLEO SOLO EPS

CLEO Systems faced a challenge in advancing their electronic prescribing app, CLEO SOLO EPS, beyond urgent care into secondary care, mental health, and community care. Recently accredited by NHS England, the app’s expansion was constrained by the existing on-premise infrastructure, a ‘private cloud’ that limited scalability. CLEO needed a cloud-based solution that could support rapid growth, improve deployment speeds, and enhance clinical efficiency, safety, and patient experience, while ensuring robust cybersecurity.

The Solution: Transitioning to a Cloud-Enabled, Scalable Architecture

The CDI programme provided CLEO Systems with a strategic framework to transition from a private to a public cloud-hosted infrastructure, enabling scalability and agility. Through collaboration with AWS, CLEO’s implementation not only includes critical multi-tenancy capabilities to support their expansion but also adheres to the AWS Well-Architected Framework to ensure optimal system performance and security.

In addition to strengthening their technological infrastructure, CLEO worked closely with UCL and AWS to explore how data could be leveraged for future research projects aimed at enhancing service delivery and prioritising further innovations. Key technical achievements included:

  • Control Tower & Landing Zone setup
  • Cloud Gateway HSCN integration
  • ECS + Fargate with cluster auto-scaling
  • Managed RDS SQL Server
  • Application Load Balancer, VPCs, and Route 53
  • GuardDuty ECS Runtime monitoring
  • CloudTrail implementation

Enhancing Scalability, Security, and Patient Outcomes

The transition to a cloud-enabled infrastructure significantly enhances CLEO’s ability to scale and accelerate deployment speeds across their platforms. These advancements improve clinical efficiency, strengthen cybersecurity, and contribute to an overall improved patient journey. By enhancing both their technological infrastructure and team capabilities, CLEO Systems is now well-positioned for future growth in both the UK and international markets.

Throughout the CDI programme, CLEO Systems benefited from robust support provided by UCL and AWS. The structured approach enabled CLEO to develop a clear strategy and prioritise key actions, with continuous guidance from technical specialists and senior management. The partnership with AWS extended beyond the programme, facilitating ongoing collaboration and access to AWS’s network of partners, providing CLEO with long-term agility and innovation potential.


CLEO Systems’ Commercial Director, Richard Burton, summarises the company’s experience with the CDI:

“Having previously worked with UCL at the IDEALondon accelerator, I was familiar with UCL’s strong approach to innovation. However, during the CDI, what impressed me most was the strength of the AWS partnership, which has extended beyond the programme. The AWS team remains highly responsive, and we look forward to building relationships with other AWS partners as well.”