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DCNU in the News December 2013

Sunday 8 December 2013 More...




Developmental Cognitive Neuroscience Journal July


Latest Quarterly Journal of:
Developmental
Cognitive Neuroscience

(Volume 7: January 2014)

2012 Impact Factor: 3.160

Baldeweg-Croft Project

Neuroimaging Investigations of Language to aid Paediatric Neurosurgical Decision-Making

We have developed a set of children-friendly tasks to investigate different aspects of language (listening, reading and speaking) during functional magnetic resonance brain imaging (fMRI). These tasks (the Panda Games) are suitable for healthy children as young as 5 years of age and children with cognitive impairment. The Panda Games are supported by themed documentation introducing children to the MRI procedure, online practice versions and practice monitoring, and a mock scanning protocol.

This project has two main aims. First, we aim to assess the reliability and accuracy of the Panda Games for presurgical language mapping in children with medically refractory epilepsy. We expect the Panda Games to improve the yield of presurgical fMRI assessments, show greater correspondence with intracranial mapping results of eloquent cortex, and offer a more extensive toolbox for pre-surgical language mapping across a range of patients and surgical procedures.

Second, using advanced functional connectivity techniques we aim to further our understanding of receptive and expressive language network development during childhood. This will include identification of critical nodes and pathways in the typical language network, as well as identification of alternative, compensatory or immature pathways supporting language across childhood.

We are currently recruiting healthy children between 5 and 16 years of age. Participants will have the opportunity to visit Great Ormond Street Hospital for fMRI scanning, will undergo intelligence and language neuropsychological assessment, and will receive a £10 gift voucher and a picture of their brain to take home! For further information or to apply please contact Louise Croft: louise.croft.09@ucl.ac.uk

pandagamesresearchtrial