All Seminars are held in the Gavin De Beer Lecture Theatre, Anatomy Building, Thursday 1-2pm
May 21: Richa Tripathi (Richardson lab) Death of an Oligodendrocyte: the if and when?
Lewis Brayshaw, (Price lab) Cadherin cell adhesion in cancer metastasis and neural progenitor cell maintenance
June 18: Anna Czarkwiani (Oliveri Lab)/ Zhe Liu (Yamamoto Lab)
Dr Yoshiyuki Yamamoto
Research in our lab focuses on understanding the molecular mechanisms underlying the generation of morphological novelties during evolution. We are using the Mexican tetra Astyanax mexicanus as a model system for studying evolution, development and regeneration.
Evolution, development and regeneration
Astyanax mexicanus exhibits both eyed surface (surface fish: Figure 1) and eyeless cave (cavefish: figure 2) populations. During the late Pleistocene (about 10,000 to 100,000 years ago), the surface fish diverged into at least 30 distinct cavefish populations in northern Mexico. Since then, the cavefish have evolved regressive characters such as degenerate eyes, a smaller optic tectum, and less pigment, but they also have evolved constructive characteristics such as a larger jaw and additional teeth, cranial neuromasts, and taste buds. We use molecular and experimental embryological techniques to study the mechanisms by which this evolution occurred. Our research mainly focuses on the following projects:
· Mechanisms and evolutionary forces of cavefish eye degeneration
· Brain evolution
· Craniofacial development and evolution
· Heart development and regeneration
If you are interested in participating in these research projects, feel free to contact us, e-mail: email@example.com
· Yoshiyuki Yamamoto E-mail: firstname.lastname@example.org
· Mathilda Mommersteeg (Postdoctoral Research Fellow): email@example.com
· Fábio Rodrigues (Student)
· Amy Munro-Faure (Student)
· Jake Wyatt (Student)
Department of Cell and Developmental Biology
University College London
London WC1E 6BT
Publications and further information
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Page last modified on 31 jul 13 14:54 by Edward D Whitfield