First Year CDB PhD Students: Mini Symposium
Tuesday 1 July, 1.30-4.10pm
Host: Yoshiyuki Yamamoto
1.45pm Francis Carpenter: “Neural Representations of Space in Connected, Perceptually Identical Compartments”
2.00pm Chris Penny: "The functional architecture of Two-Pore Channels"
2.15pm Amina Yonis: “The role of actin nucleators in the cellular actin cortex”
2.30pm Lewis Brayshaw: ”Cadherin de-adhesion in cancer”
2.45pm Agnieszka Piatkowska: “Mechanism of somite formation”
3.10pm Alan Greig: “Pertussis vaccination and dysfunction of the blood brain barrier: an in vitro study”
3.25pm Marina Teter: “The role of Wnt antagonists in synapse vulnerability”
3.40pm Gauri Bhosale: “Investigating the mitochondrial permeability transition pore as a therapeutic target in human disease”
3.55pm Lourdes Sri Raja: "Modelling Protein Signalling Pathways during Neutrophil Differentiation"
Thursday July 3rd, 12pm
Dr Gyorgy Szabadkai
g.szabadkai (at) ucl.ac.uk
I'm currently on leave, working at the University of Padua (UoP) and
establishing the UCL-UoP collaborative Mitochondrial Research Platform.
The interest of my research groups is to understand the role of mitochondria in cellular stress responses in major pathologies such as neurodegenerative disease and cancer. We use bioinformatics, biochemical, molecular biology and cellular imaging tools in collaboration with other mitochondrial biology and imaging groups at the UCL and UoP.
|Schematic outline of our research –Stress conditions, accompanying several pathologies like neurodegenerative diseases, diabetes and cancer induce adaptive responses in both the mitochondrial and ER networks. This includes an increased turnover of organelle biogenesis and degradation (autophagy). If adaptation fails, cells utilize different pathways to die. ER-mitochondrial crosstalk and transcriptional regulation of the mitochondrial proteome (biogenesis) determine both adaptive and death responses and thus will be a target of cellular stress signaling pathways.|
Lab members at UCL:
Robert Bentham (UCL COMPLeX, British Heart Foundation PhD fellow)
Julia Hill (Eisai funded PhD fellow)
Gregory Keen (Research Assistant, UCL-Eisai Therapeutic Innovation Group)
Thomas Briston (Research Assistant, UCL-Eisai Therapeutic Innovation Group)
Ronan Astin (Clinical PhD fellow)
Page last modified on 23 feb 14 17:41 by Gyorgy Szabadkai