CDB Seminars
All welcome


First Year CDB PhD Students: Mini Symposium

Tuesday 1 July, 1.30-4.10pm

Host: Yoshiyuki Yamamoto
Room 249, 2nd Floor, Medical Sciences Building
1.30pm  Lizzie Yates: "Messed up lysosomes: what’s their role in Parkinson’s disease?"

1.45pm  Francis Carpenter: “Neural Representations of Space in Connected, Perceptually Identical Compartments”

2.00pm  Chris Penny:  "The functional architecture of Two-Pore Channels" 

2.15pm  Amina Yonis: “The role of actin nucleators in the cellular actin cortex”

2.30pm  Lewis Brayshaw: ”Cadherin de-adhesion in cancer”

2.45pm  Agnieszka Piatkowska: “Mechanism of somite formation”

3.00pm  Interval

3.10pm  Alan Greig: “Pertussis vaccination and dysfunction of the blood brain barrier: an in vitro study”

3.25pm  Marina Teter: “The role of Wnt antagonists in synapse vulnerability”

3.40pm  Gauri Bhosale: “Investigating the mitochondrial permeability transition pore as a therapeutic target in human disease”

3.55pm  Lourdes Sri Raja: "Modelling Protein Signalling Pathways during Neutrophil Differentiation"


Thursday July 3rd, 12pm
Dr Shmuel Muallem, National Institutes of Health
Title: Lysosomal ion channels: form, function and dysfunction
Host: Prof Sandip Patel
Venue: Room 249, Medical Sciences Building

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Dr Gyorgy Szabadkai

Dr Szabadkai

Senior Lecturer

g.szabadkai (at) ucl.ac.uk

Office: 020 7679 7362
(Int: 37362)


I'm currently on leave, working at the University of Padua (UoP) and establishing the UCL-UoP collaborative Mitochondrial Research Platform.

The interest of my research groups is to understand the role of mitochondria in cellular stress responses in major pathologies such as neurodegenerative disease and cancer. We use bioinformatics, biochemical, molecular biology and cellular imaging tools in collaboration with other mitochondrial biology and imaging groups at the UCL and UoP.

Schematic outline of our research Stress conditions, accompanying several pathologies like neurodegenerative diseases, diabetes and cancer induce adaptive responses in both the mitochondrial and ER networks. This includes an increased turnover of organelle biogenesis and degradation (autophagy). If adaptation fails, cells utilize different pathways to die.  ER-mitochondrial crosstalk and transcriptional regulation of the mitochondrial proteome (biogenesis) determine both adaptive and death responses and thus will be a target of cellular stress signaling pathways.

Lab members at UCL:

Robert Bentham (UCL COMPLeX, British Heart Foundation PhD fellow)

Julia Hill (Eisai funded PhD fellow)

Gregory Keen (Research Assistant, UCL-Eisai Therapeutic Innovation Group)

Thomas Briston (Research Assistant, UCL-Eisai Therapeutic Innovation Group)

Ronan Astin (Clinical PhD fellow)

Page last modified on 23 feb 14 17:41 by Gyorgy Szabadkai