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UCL Institute of Cardiovascular Science

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Translating Ideas into Therapies

01 July 2021, 4:00 pm–4:50 pm

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Event Information

Open to

All

Availability

Yes

Organiser

Clare Cockerham

The global need for effective medicines is increasing, whilst the biology underlying new drug concepts is becoming increasingly complex. This meeting will outline how our research community is rising to address these challenges by following the early life cycle of new medicine concepts through 3 critical stages: 1) Identifying your target. 2) Drugging your target. 3) Gaining clinical insights. These session themes will run sequentially and blend the most exciting science from early career researchers, commercial organisations and key academic, clinical and industry leaders in the field. In addition, an interactive panel discussion will provide the opportunity to share perspectives on some of the most current and innovative routes though which to translate scientific ideas into impactful therapies. Topics in scope for this scientific program will include:

Target Identification & Validation

  • Disease-centric biology insights & dealing with increasingly complex target biology
  • Leveraging emerging platform technologies
  • Deconvoluting target hit lists

Drugging your target

  • How new drug formats are changing drug discovery
  • New concepts in pharmacology – poly-pharmacology, cellular kinetics etc
  • New models of collaborative drug discovery (panel discussion topic)

Clinical insights

  • Experimental medicine studies with proprietary and/or essential medicines
  • Examples of successful clinical translation of new medicine concepts
  • Bringing patient data insights into the discovery pipeline

Through this joint meeting, being organised by ELRIG and the BPS, we aim to bring together the research community working in the field of new medicine creation with interests in developing their translational research ideas and applying novel technologies and means of collaboration to address critical clinical needs. Join scientists from academia, pharma, biotech and CRO’s either in person or online to hear talks given by speakers at the cutting edge of their field and gain strategic insights into solutions for increasing the success of your therapeutic ideas.

About the Speaker

Professor Lucie Clapp

at UCL

Image of Professor Lucie Clapp
Lucie Clapp is Professor of Vascular Physiology, Head of Pre-clinical & Fundamental Science and Deputy Director of the UCL Institute of Cardiovascular Science. A pharmacologist and biophysicist by training, her research expertise lies in the functional properties of potassium channels and prostaglandins in the cardiovascular system and their role in bacterial infection and blood vessel remodelling. She has won numerous awards and accolades for her research, including 5 science fellowships that have supported her own personal salary and laboratory for 16 years. Through knowledge-transfer partnerships and consultancies, she has interacted with several Pharmaceutical companies for the last 20 years, raising funds to develop novel therapeutic strategies for treating pulmonary hypertension, thus bringing an understanding of the commercial world alongside academia. In 2017, she was awarded the AstraZeneca Prize for Women in Pharmacology. Lucie Clapp has a leadership role as a trustee of UCL, elected in 2015 by the professorial membership of UCL to serve on Council, the governing body which oversees the finances, management and administration of the university.