Centre for Cardiometabolic and Vascular Science

The core goal of the Centre for Cardiometabolic and Vascular Science (CCVS) is to understand the biological and molecular mechanisms that control a) lipid metabolism, inflammation and tissue damage in cardiometabolic and autoimmune diseases and b) the functions of blood vessels to translate this knowledge into novel therapies for cardiovascular and other human diseases.

A major focus of our research is understanding the transcriptional regulation of lipid metabolism and its impact on inflammatory pathways by lipid-activated nuclear receptors and how the angiogenic cytokine, VEGF, signals endothelial cells in blood vessels to mediate its vital functions in vertebrates.

Head of Centre

Professor Ines Pineda Torra

Principal Investigators

Professor John Martin
Professor Ian Zachary

Research

A major focus of research in this centre is Vascular Endothelial Growth Factor (VEGF).

Teaching

The Centre for Cardiometabolic and Vascular Science sits within the Department of Experimental and Translational Medicine, and is part of the Division of Medicine. It supervises the work of PhD students, organises and contributes to several distinguished modules within the School of Life and Medical Sciences (SLMS). The Centre is willing to hear from prospective students at any time.

Publications

View publications by members of Cardiometabolic and Vascular Science staff.

Techniques

For more details and interest in using these techniques, please contact the appropriate researcher.

News and Events

We are pleased to welcome and host Professor Anders Gabrielsen from Karolinska Institute (AstraZeneca) In Sweden. Anders will be visiting and presenting his research with an exciting talk based on anti-inflammatory cardiovascular drug developemnt on the 24th October 2019. We look forward to his visit.

New dates In June 2020 to be anounced shortly for our Essential Lab Skills and Molecular Biology Techniques Workshop: from Theory to Bench. The four-day course which has been developed by the Division of Medicine will teach you a wide range of techniques used in the lab and is CPD accredited. Places are limited and concessions are availible to UCL staff and students. Please click for more details.

In April, we were pleased to welcome and host Professor Elisabetta Dejana, Professor of General Pathology, University of Milan / Professor at the Department of Immunology, Genetics and Pathology, Uppsala University, Sweden. Elisabetta Dejana is a cell biologist and expert on regulation of the vascular system development, she directs the new strategies to inhibit tumor angiogenesis research unit at IFOM, which focuses on development of tumor vasculature.

Last year, members of the CCVS in the Division of Medicine had designed the cover for the American Heart Association monthly at ATCB. This cover was up for an award. Please take a moment to click and vote for our faboulous August cover of the ATVB made by our colleagues in CCVS.