UCL Cancer Institute


Facility Oversight

Professor John Hartley
Professor John Hartley

Facility Head

Professor John Hartley is the Facility Head and has overall responsibility for all conduct of work performed within the UCL ECMC GCLP Facility. Professor Hartley is Professor of Cancer Studies at UCL, Scientific Lead of UCL ECMC. He is also Chair of CRUK Centre for Drug Development Protocol Safety and Review Board.

Dr Helen Lowe
Dr Helen Lowe

Facility Manager

Responsibilities include staff training, equipment provision and maintenance, generation of Laboratory Agreements and the Facility finances. Dr Lowe works with the QA Manager, Document Controller and Archivist, to ensure continual improvement of the Quality Management System, and the generation, maintenance and archiving of clinical trial documentation.

Dr Victoria Spanswick
 Dr Victoria Spanswick

Study Manager

Provides scientific contributions in the translational aspect and protocol development of clinical trials and studies within a Good Clinical Laboratory Practice (GCLP) environment.
Oversees all aspects of clinical trial implementation, sample analysis and data integrity within the Facility from start up, during active trial to final data reporting.

As per the GCLP guidelines, the Facility staff includes Analytical Project Managers and Analysts. The Analytical Project Managers have responsibility for the overall conduct and reporting of the individual studies being performed in the laboratory, while the Analysts conduct the analytical work in accordance to GCLP, and to ensure the quality of their work. A document controller and an archivist also have defined roles within the Facility.

All the GCLP Facility staff undergo Good Clinical Practice (GCP), Good Clinical Laboratory Practice (GCLP), Human Tissue Act (HTA), Information Governance/Data Security and Quality Management System training upon joining. Further training is also provided, commensurate with the roles and responsibilities of the staff, in the necessary Standard Operating Procedures, equipment and techniques used for sample analysis. Staff also attend relevant conferences, meetings and workshops.

Facility staff

  • Leah Ensell, Senior GCLP Facility Analyst
  • Yashma Pathak, GCLP Facility Analyst
  • Nas Mahmoud, GCLP Facility Analyst
  • Sharyar Hadi, GCLP Facility Analyst

CRUK Centre for Drug Development Biomarker Centre

  • Riaz Jannoo, Post-Doctoral Fellow
  • Angeliki Karamani, Research Assistant
  • Ridesh Rai, Research Technician

Cancer Institute ECMC Quality Manager

  • Melanie Fearon


Staff phot