Immunotherapy discovery a step towards treating T cell cancers

Researchers have discovered a new way of potentially treating mature T cell cancers using immunotherapy. The study, published in Nature Medicine, demonstrates how chimeric antigen receptor (CAR) T cells can be used to selectively target cancerous T cells.

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New ovarian cancer drug based on UCL research

A new drug to delay the spread of ovarian cancer, which was developed from UCL research, has been licensed for use in the UK. Professor Jonathan Ledermann, who led the research, said the drug was a “critical milestone” in managing the disease if the cancer recurs after chemotherapy.

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Tumour Heterogeneity Team wins Cancer Research UK Translational Cancer Research Prize 2017

The Tumour Heterogeneity Team, led by Professor Charles Swanton, has been awarded the Cancer Research UK Translational Research Prize at the National Cancer Research Institute (NCRI) conference 2017. This prize recognises the cutting edge breakthroughs of an outstanding research team that has united in the quest to ensure scientific discoveries benefit patients and the public.

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Osimertinib shows promise as new standard-of-care treatment for advanced lung cancer

Positive results from the phase-three FLAURA clinical trial show significant improvement in progression free survival in patients with EGFR-mutated advanced non-small cell lung cancer treated with a drug called Osimertinib, compared to patients treated with standard-of-care drugs. The trial data, published in the New England Journal of Medicine (NEJM), demonstrate the potential of Osimertinib to change current clinical practice and improve patient outcomes.

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Experimental model to study the development of brain cancer in children

Researchers from UCL, the German Center for Neurodegenerative Diseases (DZNE) and McGill University, Montreal have published details of a novel laboratory model that replicates the hallmarks of paediatric brain cancer. The research results, published in Cancer Cell, could pave the way for a better understanding of processes driving the development of cancer.

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