CRUK-UCL and Cancer Domain Multidisciplinary Seminar Series

Metallic nanoparticles have demonstrated promise in delivering more targeted radiotherapy in pre-clinical studies; and, more recently, metal oxide nanoparticles have shown similar promise in benchtop studies. As well as demonstrating radiosensitiser properties to potentially enhance treatment outcomes, these materials can be designed as imageable under X-ray and MRI to better guide the treatment beam. In this presentation the first speaker will discuss the applications of nanoparticles in pre-clinical imaging and radiotherapy studies, including computational modelling of nanoparticle-radiation interactions, a novel nanoparticle imaging platform and in vitro studies demonstrating radiotherapy enhancement. The second speaker will discuss recent translational research into metal-oxide nanoparticles which has led to clinical applications, and will comment on the challenges and potential benefits of bringing theranostic nanoparticles into clinical use.

Further information

• Dr Kate Ricketts academic profile
• Prof Quentin Pankhurst academic profile