Biomedical Research Unit (BRU)

NIHR Biomedical Research Units were discontinued in April 2017 and the dementia research programme was renewed as a dementia theme within the Biomedical Research Centre. This website is therefore archived and visitors are redirected to

Biomedical Research Unit

The Queen Square Dementia BRU focuses on young onset dementias in order to achieve our aims of developing new methods of diagnosis and treatment.

Young onset Alzheimer’s disease and other degenerative dementias often occur on an inherited (autosomal dominant) basis with the same clinical features as non-inherited (sporadic) disease. Identification of the mutated genes causing the dementia and longitudinal study of individuals who carry the gene create a window on the disease process.

In 2012 the National Institute for Health Research (NIHR) created four Dementia Biomedical Research Units, that have been working in close collaboration to support experimental medicine in dementia and to help meet the Prime Minister's Dementia Challenge.


The BRU programme comprises four research areas:

Dementia poses one of the greatest challenges facing society - the loss of the mental faculties that define us as humans is a personal and family tragedy. At a society level it presents a potential financial disaster as we face an increasingly aged population.

Page last modified on 31 may 18 12:51