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New insights into the treatment of ALS: MIROCALS clinical trial results published in The Lancet
Results of the MIROCALS (Modifying Immune Responses and Outcomes in ALS) clinical trial are published today in The Lancet.
12 May 2025

‘Healthy fats’ could protect against motor neurone disease
Enhancing levels of ‘healthy fats’ like omega-3s in the brain could be beneficial in motor neurone disease (MND) finds a new study in fruit flies and brain cells, led by UCL Queen Square Institute of Neurology researchers.
25 Feb 2025

New short film showcases progress in Motor Neuron Disease research at UCL
A new short film documenting the remarkable progress towards a treatment for Motor Neuron Disease (MND), also known as ALS, has been launched.
11 Feb 2025

UCL spinout launches with $101 million funding for motor neurone disease treatments
Trace Neuroscience, a UCL spinout biopharmaceutical company, has received $101m (£78m) in Series A funding, to help develop potential treatments for the most common form of motor neurone disease.
13 Nov 2024

Researchers develop way to selectively target diseased cells in Motor Neuron Disease
Researchers at the Francis Crick Institute and the UCL Queen Square Institute of Neurology have developed DNA molecules which contain ‘invisibility cloak’ sequences, preventing healthy cells from reading the messages they contain.
04 Oct 2024

Dr Rubika Balendra wins the European Network to Cure ALS (ENCALS) Young Investigator Award 2024
During the ENCALS meeting 2024 in Stockholm, Sweden, Prof. Ammar Al-Chalabi awarded two bright researchers: Dr. Rubika Balendra received the gold medal and Dr. Ratko Radakovic received silver.
01 Jul 2024

Protective response to early changes in ALS and FTD
A new study led by Professor Adrian Isaacs (UCL Queen Square Institute of Neurology and UK DRI at UCL) provides fresh insight into early changes that occur in the brains of people with ALS and FTD, and reveals a response in cells that protects against neurodegeneration
29 Feb 2024

Unusual RNA structures could be targets for new ALS treatments, study shows
Investigating strange forms of ribonucleic acid (RNA) associated with the formation of aggregates in the brains of ALS patients could lead to new avenues for treatments, a study involving UCL researchers has revealed.
21 Dec 2023

Professor Malaspina part of team awarded the Healey International Prize for Innovation in ALS
Professor Andrea Malaspina (Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology) is part of a team of researchers from the UK and US awarded the Healey International Prize for Innovation in ALS.
14 Dec 2023

Investment in new Patani Lab research to unravel the impact of DNA damage in Motor Neuron Disease
We are pleased to announce that My Name’5 Doddie Foundation recently welcomed Professor Rickie Patani of the Francis Crick Institute and UCL to their growing list of Foundation-funded researchers, working to help them achieve their vision of a world free of MND.
24 Nov 2023

New documentary highlights pioneering scientific research into new target for treatment of MND
A new documentary has been released which follows a key discovery made by researchers at UCL Queen Square Motor Neuron Disease Centre that suggests a promising target for new treatments to tackle motor neuron disease (MND), a terminal condition.
10 Nov 2023

New research institute to accelerate the search for a cure for MND
A new research institute to accelerate the search for a cure for motor neuron disease (MND, also known as ALS), launches today in London.
03 Nov 2023

Donor motor neurons could restore muscle function in amyotrophic lateral sclerosis (ALS)
Scientists led by UCL Queen Square Institute of Neurology have detailed how a combination of grafted replacement motor neurons and optical nerve stimulation – using light to activate neurons – can improve muscle function in a highly aggressive mouse model of ALS.
23 Aug 2023

Scale of disorder underpinning Motor Neuron Disease much larger than previously thought
Hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), finds a new study by researchers at UCL Queen Square Institute of Neurology and the Francis Crick Institute.
23 Jul 2023

New programme to move potential MND drugs into clinical trials faster
A ground-breaking experimental medicine programme that will enable researchers to more rapidly screen potential drugs in people with motor neuron disease (MND, also known as ALS), is announced today on Global MND Awareness Day.
21 Jun 2023
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