From Connectomic Deep Brain Stimulation toward the 'Human Dysfunctome': Dr Andreas Horn

About the Speaker

Dr. Horn is the Schilling Professor for Computational Neurology at the University of Cologne, where he founded the Network Stimulation Institute, and Associate Professor of Neurology at Harvard Medical School. He also serves as Director of DBS Research at Brigham and Women’s Hospital and Director for Connectomic Neuromodulation Research at Massachusetts General Hospital. He is the creator of Lead-DBS, an open-source toolbox used by thousands of researchers worldwide to localise deep brain stimulation electrodes and analyse stimulated brain networks. His work has been recognised with the Heinz Maier-Leibnitz-Preis, the International Brain Stimulation Early Career Award, and consistent recognition as a Clarivate Highly Cited Researcher.

About the Talk

Brain disorders manifest along a spectrum of symptoms involving disruptions in mood, cognition, or motor function - symptoms that originate from dysfunctions of specific brain circuits, or ‘circuitopathies.’ In this talk, Dr. Horn will review the effects of deep and superficial brain stimulation on the human connectome, covering insights across movement disorders (Parkinson’s disease, dystonia, essential tremor), neuropsychiatric conditions (Tourette syndrome, Alzheimer’s disease), and psychiatric disorders (OCD, depression). He will discuss how findings in seemingly disparate diseases can cross-inform treatment targets, and how connectomic methods are being leveraged to study complex behavioural traits such as risk-taking and impulsivity.

All faculty, researchers, clinicians, and students are warmly invited to attend.

For further enquiries, please contact Himanshu Tyagi at h.tyagi@ucl.ac.uk.