Brain Meeting: Terence Sanger

Prof Andreas Nieder, Institute of Neurobiology, Dept. of Biology, University of Tübingen, Germany.

Please contact ion.fil.brainmeetings@ucl.ac.uk for a Zoom link.

Our understanding of numbers, vital to our scientifically and technically advanced culture, has deep biological roots. Research across developmental psychology, anthropology, and animal cognition suggests that our ability to count symbolically arises from more primitive non-symbolic number representations. By studying single-neuron activity in associative brain areas of awake human patients and monkeys, we aim to uncover the physiological principles behind how numbers are represented in the brain. In both species, we’ve identified “number neurons” that encode set sizes regardless of how the stimuli are presented. These neurons play a crucial role in processing numerical information during goal-directed behavior. Moreover, investigating how numbers are processed in working memory offers insights into high-level cognitive control functions. Comparative research in numerical cognition is uniquely positioned to unravel the brain processes enabling humans to transition from nonsymbolic to symbolic representations, a hallmark of our species.