Welcome to SMB
The Department of Structural and Molecular Biology (SMB) provides a stimulating and diverse research and training environment of international standing in cutting edge, modern Biochemistry.
Our broad set of skills and high-quality research allows us to approach fundamental biological and medical problems at the atomic, molecular, cellular and organism level.
This vision is enhanced via our partnership with the Department of Biological Sciences at Birkbeck College and, together, we comprise the Institute for Structural and Molecular Biology (ISMB).

A ribbon diagram of the structure of the outer membrane protein complex of a type IV secretion system. These large multi-subunits protein complexes are used by Gram-negative bacteria in a variety of processes involving a transport of proteins or DNA across the membranes. Chandran et al 2014. Nature. 462:1011-1015.
Our people and our research
SMB Research Themes

Microbiology & Synthetic Biology

Metabolism and Cancer

Proteins, Membranes & Trafficking

Gene Expression & RNA Biology

AI and Deep Learning
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Other Training and Resources

Find resources and support for promoting student and staff wellbeing

Find out about sustainability initiatives for labs and individuals
Contact Us
Department of Structural and Molecular Biology
Division of Biosciences
UCL Darwin Building
Gower Street
London WC1E 6BT
General Enquiries tel: +44 (0)20 7679 2308, email: tabitha.owen@ucl.ac.uk
Postgraduate Enquiries email: biosciences.pgr.admin@ucl.ac.uk
Undergraduate Enquiries email: biosciences-admissions@ucl.ac.uk
The majority of our laboratories and research spaces are located in the UCL Darwin Building on Gower Street, formerly the site of 'Macaw Cottage', a residence of Charles Darwin's.
The main reception to the building is accessed via Darwin Walk, off Malet Place, entered via Torrington Road.