Current Members

 

Kamila Kamuda
Research Fellow
Email, ORCID, UCL profile

I joined the Brodsky Lab in January 2024 as a post-doctoral researcher in order to investigate the involvement of CHC22 clathrin heavy chain in the trafficking of GLUT4 glucose transporter in muscle cells. In my research, I will use various cellular structural biology techniques to study the distribution and morphology of proteins in skeletal muscle fibres. Prior to joining the lab, I completed a PhD in the laboratory of Prof David Lomas, where I studied the effects of the pathological Z mutation of alpha-1-antitrypsin on ultrastructural changes within the cell.

Alyce McClellan
Research Fellow
Email, ORCID, UCL profile

My research in the Brodsky lab is focused on further characterising the role of clathrin heavy chains (CHC17 and CHC22) in GLUT4 trafficking. I am particularly interested in the relevance of these pathways to the development of Type 2 diabetes. I will be characterising the changes in clathrin heavy chain mechanisms after induction of insulin resistance in cultured human muscle cells. Before joining the lab, I completed my PhD at the University of Cambridge studying the genetic and molecular causes of obesity in Dr. Eleanor Raffan's canine genetics lab. Prior to this, my research experience included studying tendon injury in 3D embryonic stem cell models as well as microtubule formation.
 

 

Daowen (Ivanna) Yin
PhD Student
Email, ORCID, UCL profile

I joined the Brodsky lab in 2021 as a Masters student and worked on the differential binding of clathrin light chains (CLCs) and sorting nexin 5/6 (Snx5/6) to clathrin heavy chain 22 (CHC22) in vitro. In July 2022, I graduated with a degree in MSci Biochemistry from UCL and started my PhD research in September. My PhD project focuses on identifying functional clathrin assembly contacts in CHC17 and CHC22 clathrin using recombinant approaches and biochemical analysis.

 

 

Callum Emin
MSci Student
Email, LinkedIn

I joined the Brodsky Lab in August 2024 as a Masters student. I am in the final year of my degree and I am planning to graduate from UCL with a degree in MSci Biochemistry in September 2025. My masters project focuses on "checking if it possible to study the GLUT4 trafficking pathway in the absence of CHC22 by detecting changes in its glycosylation pattern?". This will help elucidate the journey of GLUT4 through the cell. Therefore, I can help reinforce of the concept of CHC22 causing GLUT4 to immediately from glucose storage vesicles instead of following the normal secretory pathway through the Golgi apparatus.

 

 

Nita Rexhepi
MRes Student
Email, LinkedIn

I joined the Brodsky lab in October 2024 as a Biosciences MRes student in the cell biology stream. Using an array of cell biology techniques, I will be studying how membrane contact sites are involved in the trafficking of glucose transporter, GLUT4, and ultimately how this connects to clathrin. Previously, I completed my bachelor’s degree at Queen Mary, University of London where I conducted a research project in Dr Wilkinson’s lab looking at whether DNA glycosylase, MYH, is essential for the viability of sleeping sickness inducing parasite, Trypanosoma brucei.

 

 

Connor Seery
MRes Student
Email, LinkedIn

I joined the Brodsky lab in August 2024 as a master’s student after completing my undergraduate degree in Biological sciences at the University of Warwick. My research is focused on the evolution of structure and function of clathrin light chain (CLC). I am using a variety of bioinformatic and biochemical approaches to find the most evolutionarily conserved parts of CLCs in species throughout the tree of life.

 

Former (UCL) group members

• Hermione Allen (Masters Student)
  Subsequent Position: PhD Student, UCL Cancer Institute, London
• George Bates (PhD Student and Research Associate)
  Subsequent Position: Senior Scientist, AstraZeneca, Cambridge
• Kit Briant (Research Associate and Lab Manager)
  Subsequent Position: Analyst, Empartners, London
• Will Bultitude (Research Associate)
  Subsequent Position: Editor, Scientific Reports, London
• Alice Burke (Research Technician)
  Subsequent Position: PhD Student, Imperial College London
• Marine Camus (Lab Manager)
  Subsequent Position: Scientific Project Manager, IMI-NECESSITY, Inserm, Paris 
• Stéphane Camus (Research Associate)
  Subsequent Position: INSERM investigator, Paris
• Yu Chen (Research Associate)
  Subsequent Position: Research Scientist, Sanofi (Kymab), Cambridge
• Philip Dannhauser (UCL Excellence Research Fellow)
  Subsequent Position: Group Leader, Miltenyi Biotec, Cologne
• Lucia Fernandez Barreiros (Masters Student)
  Subsequent Position: Consulting Analyst, IDEA Pharma, London
• Carmen Figueras-Novoa (Masters Student)
  Subsequent Position: PhD Student, Francis Crick Institute, London
• Letizia Filippi (Masters Student)
  Subsequent Position: PhD Student, Francis Crick Institute, London
• Lauren Foltz (Research Associate)
  Subsequent Position: Analyst, Empartners, Pennsylvania, USA
• Josh Greig (Research Associate)
  Subsequent Position: Research Associate, Zammit Lab, King's College London
• Pallavi Ramsahye (Research Technician)
  Subsequent Position: Higher Scientific Officer, Institute of Cancer Research (Sutton), London
• Lisa Redlingshöfer (PhD Student and Research Associate)
  Subsequent Position: Research Associate, Max Planck Institute of Molecular Cell Biology & Genetics, Dresden
• Amanda Sadacca (Lab Manager)
  Subsequent Position: Director, Awards, New York Academy of Sciences
• Wing Yan Siu (Masters Research Student)
  Subsequent Position: DPhil Student, Oxford University
• Max Walmsley (Research Technician)
  Subsequent Position: PhD Student, University of Manchester
• Xinyi Zhang (Masters Student)
  Subsequent Position: M.Sci Student in Business Analytics at Simon Business School, University of Rochester, USA.