Research Facilities

Here we list all the Research Facilities in Biosciences. The Facilities are managed by expert support staff who can also provide training and advice on experimental set up. The Facilities  are overseen by an academic or an academic steering group responsible for ensuring that the Facility is operated and equipped for maximum benefit to the research community. In addition, the School of Life and Medical Sciences is currently establishing a number of Platform Technologies that will be available for all staff in the School. These will be added to the list below as they come on line.

Electron Microscopy Mass Spectrometry
The main Biosciences EM Facility has a number of Transmission Electron Microscopes (TEM) and Scanning Electron Microscopes (SEM), including a new field emission scanning microscope. The Facility also contains a sample preparation laboratory, with a range of preparation equipment. We run as a multi user facility or on a service basis, which allows users the choice as to what level of involvement they wish to have. Mass spectrometry is an analytical tool used for measuring the molecular mass of a sample. For proteins of size up to about 50,000 Da, molecular masses can be measured to within an accuracy of 0.01% of the total molecular mass of the sample i.e. within a 4 Daltons (Da) or atomic mass units (amu) error for a sample of 40,000 Da. This is sufficient to allow minor mass changes to be detected, e.g. the substitution of one amino acid for another, or a post-translational modification.
Fish Facility Imaging

The UCL zebrafish facility is currently comprised of four separate multi-rack systems and several standalone and bench top systems housed in five separate rooms. The facility currently holdings around 400 genetically distinct lines - currently approximately 70,000 fish, with a maximum capacity of 100,000 fish.

The Imaging Facilities comprise a suite of confocal, 2-photoin luminescence, wide field and conventional imaging systems. These systems will cover most imaging requirements for cells and tissues. There is a range of upright and inverted systems with various stage configurations. Environmental chambers are available on some systems making it possible to perform experiments over long time courses. More specialised imaging requirements including FRET, FLIM and FRAP can also be performed on some of the systems.
Electronic Workshops Mechanical Workshop
The Electronics Workshop provides a design / prototype / manufacture service for both analogue and digital electronic equipment. In addition, the fault finding and repair of ready built equipment / apparatus is undertaken. The Mechanical Workshop provides a professional design and production service to the medical sciences and has a reputation for quality and excellence. Experienced staff can give guidance on design aspects as required. Service is generally tailored to suit individual requirements to produce innovative and sophisticated research projects.
Molecular Biology Molecular Biophysics
Molecular biology facilities exist in a number of locations. Each Unit carries out a number of techniques and services. For charging policies please contact the lead in each Unit. In addition to these local facilities recent developments in platform technologies at UCL provide staff in Biosciences with a wide range of molecular biology facilities (see UCL Genomics). The aim of the UCL/Birkbeck ISMB Biophysics Centre is to offer biophysical instrumentation and expertise to scientists based in London or beyond. A variety of equipment is available for equilibrium and kinetic studies of proteins, nucleic acids, small molecules and their interaction
Molecular Interactions Facility Stores

The Division of Biosciences Stores stocks a wide range of laboratory consumables, chemicals and stationery. Stores also receives deliveries, arranges couriers and equipment quotations and provides purchasing, invoicing, dry ice and recycling services.

UCL Genomics and Bioinformatics UCL Computing

UCL Genomics provides complete quality assessments of all samples throughout preparation & processing, in addition to complete downstream data QC & analysis for each microarray experiment.

  • Sample quality control: Bioanalyer traces and Nanodrop quantification
  • Detailed analysis of raw data: MvA plots, signal distribution box-plots, background and signal-to-noise measurements, percent called, and more
 The Research Computing community at UCL aims to facilitate a collegial and collaborative approach to the provision, management and development of services and infrastructure for capacity and capability High Performance Computing (HPC), and to exploit interdisciplinary synergies across the wide spectrum of research excellence at UCL

UCL Chemical Biology
The UCL Centre for Chemical Biology aims to create a dedicated facility for small molecule synthetic chemistry with the express purpose of developing small molecule probes in collaboration with biomedical scientists for use within academia. The Centre is developing diverse chemical libraries that can be used for screening, platform technologies to aid novel rapid synthetic routes for specific purposes. The Chemical Biology laboratory has expertise in molecular synthesis, such as the creation of novel sodium channel blockers and SMoCs - Small Molecule Carriers for transporting proteins into cells.

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Page last modified on 09 jan 12 14:36