Here we list all the Research Facilities in Biosciences. The Facilities are managed by expert support staff who can also provide training and advice on experimental set up. The Facilities are overseen by an academic or an academic steering group responsible for ensuring that the Facility is operated and equipped for maximum benefit to the research community. In addition, the School of Life and Medical Sciences is currently establishing a number of Platform Technologies that will be available for all staff in the School. These will be added to the list below as they come on line.
The main Biosciences EM Facility has a number of
Transmission Electron Microscopes (TEM) and Scanning Electron Microscopes
(SEM), including a new field emission scanning microscope. The Facility also
contains a sample preparation laboratory, with a range of preparation
equipment. We run as a multi user facility or on a service basis, which allows
users the choice as to what level of involvement they wish to have.
Mass spectrometry is an analytical tool used for measuring the
molecular mass of a sample. For proteins of size up to about 50,000 Da,
molecular masses can be measured to within an accuracy of 0.01% of the
total molecular mass of the sample i.e. within a 4 Daltons (Da) or
atomic mass units (amu) error for a sample of 40,000 Da. This is
sufficient to allow minor mass changes to be detected, e.g. the
substitution of one amino acid for another, or a post-translational
The UCL zebrafish facility is currently
comprised of four separate multi-rack systems and several standalone and bench
top systems housed in five separate rooms. The facility currently holdings around
400 genetically distinct lines - currently approximately 70,000 fish, with a maximum capacity of 100,000
The Imaging Facilities comprise a suite of
confocal, 2-photoin luminescence, wide field and conventional imaging systems.
These systems will cover most imaging requirements for cells and tissues. There
is a range of upright and inverted systems with various stage configurations.
Environmental chambers are available on some systems making it possible to
perform experiments over long time courses. More specialised imaging
requirements including FRET, FLIM and FRAP can also be performed on some of the
The Electronics Workshop provides a design / prototype / manufacture
service for both analogue and digital electronic equipment. In
addition, the fault finding and repair of ready built equipment /
apparatus is undertaken.
The Mechanical Workshop provides a professional design and production
service to the medical sciences and has a reputation for quality and
excellence. Experienced staff can give guidance on design aspects as
required. Service is generally tailored to suit individual requirements
to produce innovative and sophisticated research projects.
Molecular biology facilities exist in a
number of locations. Each Unit carries out a number of techniques and services.
For charging policies please contact the lead in each Unit. In addition to
these local facilities recent developments in platform technologies at UCL
provide staff in Biosciences with a wide range of molecular biology facilities
(see UCL Genomics).
The aim of the UCL/Birkbeck ISMB Biophysics Centre is to offer
biophysical instrumentation and expertise to scientists based in London
or beyond. A variety of equipment is available for equilibrium and
kinetic studies of proteins, nucleic acids, small molecules and their
Molecular Interactions Facility
UCL Genomics provides complete quality assessments of all samples
throughout preparation & processing, in addition to complete
downstream data QC & analysis for each microarray experiment.
- Sample quality control: Bioanalyer traces and Nanodrop quantification
- Detailed analysis of raw data: MvA plots, signal distribution
box-plots, background and signal-to-noise measurements, percent called,
The Research Computing community at UCL aims to facilitate a collegial
and collaborative approach to the provision, management and development
of services and infrastructure for capacity and capability High
Performance Computing (HPC), and to exploit interdisciplinary synergies
across the wide spectrum of research excellence at UCL
The UCL Centre for Chemical Biology aims to create a dedicated facility
for small molecule synthetic chemistry with the express purpose of
developing small molecule probes in collaboration with biomedical
scientists for use within academia. The Centre is developing diverse
chemical libraries that can be used for screening, platform
technologies to aid novel rapid synthetic routes for specific purposes.
The Chemical Biology laboratory has expertise in molecular synthesis,
such as the creation of novel sodium channel blockers and SMoCs - Small
Molecule Carriers for transporting proteins into cells.
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Page last modified on 09 jan 12 14:36