Increasing numbers of couples (1 in 7) require some medical assistance to become pregnant during their reproductive years. Some of this increase is a result of delaying the age of first pregnancy. Maternal age is one of the major factors affecting fertility. The problem is known to be a result of eggs and early embryos having an increased number of chromosomal abnormalities. Research in the Laboratory of Oocyte and Embryo Development focusses on understanding what makes a healthy egg, why fertility reduces with age and how environmental insults such as radiation, toxins, and abnormal levels of hormones can effect fertility through acting on the egg.

Research Areas

The research areas listed below, detail further information about experts in those research areas:

Research Themes

Theme Case Study

We are currently assessing how eggs monitor and detect problems with the division of chromosomes during meiosis. Understanding the molecules involved in detecting chromosomal errors and the metabolites necessary to fuel the eggs energy supply will provide new approaches to improving IVF treatment.

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