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UCL Division of Biosciences

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Dr Martin Stocker

Dr Martin Stocker

Reader in Molecular and Cellular Neuroscience

Neuro, Physiology & Pharmacology

Div of Biosciences

Joined UCL
1st Dec 2000

Research summary

The laboratory studies several aspects of potassium channel molecular physiology, combining molecular biology with electrophysiology, histochemistry and biochemistry. In particular, we investigate the mechanisms responsible for targeting, clustering and regulation of calcium-activated potassium channels to understand how these channels influence the signal processing of neurons in the central nervous system. A second line of research concerns the structural and functional properties of the modulatory potassium channel subunits, which comprise one-fourth of all voltage-gated K+ channels. The aim is to understand the physiological relevance of these ion channels in particular in the central nervous system. Finally, we are screening and characterizing novel drugs and toxins acting as highly selective blockers or openers of potassium channels. These molecules are invaluable tools to define the function of different potassium channels.

Education

Ruhr-Universitat Bochum
Doctorate, Doctor rerum naturalium | 1991
Ruhr-Universitat Bochum
First Degree, Diplom | 1989
Publications