Key Publications from the IHA. July-Dec 2024

Hull AJ, Atilano, ML, Kinghorn K, et. al. Ceramide lowering rescues respiratory defects in a Drosophila model of acid sphingomyelinase deficiency. Human Molecular Genetics

Zhang A, Zhang B, Chapman H, Gems D et. al. Characterization of effects of mTOR inhibitors on aging in C. elegans Journals of Gerontology A

Magalhães P, Virk R, Gems D Epigenetic clocks and programmatic aging Ageing Research Reviews

Gems D and Kern C. Biological constraint, evolutionary spandrels and antagonistic pleiotropy Ageing Research Reviews

Gems D et. al. Inflated expectations: the strange craze for translational research on aging EMBO Reports

Anver S, Sumit A, Alic N, Bähler J, et. al. Ageing-associated long non-coding RNA extends lifespan an reduces translation in non-diving cells EMBO Reports

Partridge L, et. al. Obesity and risk of diseases associated with hallmarks of cellular ageing: a multicohort study. Lancet Healthy Longev.

Anver S, Smermova T, Alic N, et. al. Disruption of tRNA biogenesis enhances proteostatic resilience, improves later-life health and promotes longevity. PLOS Biology

Enrinjeri AP, Labbadia J et. al. HSF-1 promotes longevity through ubiquili-1-dependent mitochondrial network remodelling. Nature Communications