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Professor David Gems awarded prestigious WT Investigator Award

20 June 2019

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Congratulations to Professor David Gems on his Wellcome Trust Investigator Award, ‘Discovering principles of senescent pathophysiology using a simple animal model’. The major award of £1,153,902 will investigate how pathways that affect lifespan act to control such late-life run on, how different treatments that extend lifespan act by altering different life-limiting diseases, and the extent to which mechanisms involved affect other species.

Ageing is now the main cause of disease worldwide. Understanding its primary causes in C. elegans should reveal basic principles about causes of late-life disease, and inform future medical treatments to improve late life health. This work will build on his recent demonstration that a new paradigm can explain origins of C. elegans diseases of ageing: unnecessary continuation of growth-related processes in later life.