UCL Division of Biosciences


New cell movement process key to understanding facial malformations published in Science

19 October 2018

Cell and Developmental Biology

The embryonic stem cells that form facial features, called neural crest cells, use an unexpected mechanism of moving from the back of the head to the front to populate the face, finds a new UCL-led study.
The researchers say their findings could help understand how facial defects form, bringing scientists one step closer to repairing craniofacial malformations in the embryo.

Read full article: New cell movement process key to understanding and repairing facial malformations
Read full paper: Supracellular contraction at the rear of neural crest cell groups drives collective chemotaxis
Authors: Adam Shellard, András Szabó, Xavier Trepat, Roberto Mayor