CDB's Szabadkai team receives Wellcome Trust Pathfinder Award to study mitochondrial subtypes of breast cancer
28 November 2016
The grant will fund a postdoctoral bioinformatician/cell biologist to develop and carry out initial validation of a novel bioinformatic approach to classify luminal breast cancers according to their nuclear encoded mitochondrial gene expression profiles. The team will test the hypothesis that the classification informs on chemosensitivity of these tumours using patient material and in vivo models. The classification method is based on the massively correlated biclustering (MCBiclust) algorithm previously developed by Robert Bentham in COMPLeX under the supervision of GS and KB.