GEE-IHA Joint Seminar - Professor Joao Pedro de Magalhaes, University of Liverpool
10 November 2021, 12:00 pm–1:00 pm
Title: 'Computational Biology Approaches for Research on Ageing'
Event Information
Open to
- UCL staff | UCL students | UCL alumni
Availability
- Yes
Organiser
-
Amy Godfrey
Location
-
Hybrid Zoom MeetingG08 David Davies LT, Roberts Building---
Academic Host:Jürg Bahler
Abstract: Ageing has a profound impact on human society and modern medicine, yet it remains a puzzle of biology. Considerable progress has been made in model organisms with many genes shown to regulate ageing. It is now necessary, however, to investigate how these genes work as an aggregate to modulate the ageing process. In this talk, I will present our network and systems biology studies of ageing to gain insights on which processes and pathways impact on ageing and age-related diseases. We also applied computational and integrative methods to dietary and pharmacological manipulations of ageing, revealing new life-extending drugs. Lastly, I will discuss our work in sequencing and analyzing the genome of long-lived mammals, like the naked mole-rat and the bowhead whale, to identify genes and pathways under selection in long-lived lineages that may be part of longevity assurance mechanisms.
About the Speaker
Prof Joao Pedro de Magalhaes
Principal Investigator at University of Liverpool
Ageing has a profound impact on human society and modern medicine, yet it remains a major puzzle of biology. The goal of my work is to help understand the genetic, cellular, and molecular mechanisms of ageing. In the long term, I would like my work to help ameliorate age-related diseases and preserve health. No other biomedical field has so much potential to improve human health as research on the basic mechanisms of ageing.
https://www.liverpool.ac.uk/life-course-and-medical-sciences/staff/joao-de-magalhaes/