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The aim of our research is to discover genes and mechanisms that determine the rate of ageing. We collaborate with other laboratories to determine if these processes show evolutionary conservation. Most of our work is conducted with the fruit fly Drosophila melanogaster through comparison with C.elegans and then with the mouse.
Our work focuses particularly on the insulin/IGF-like signalling pathway, dietary restriction and resistance to stress. We are interested also in the physiological mechanisms that force organisms to make trade-offs, such as that between high nutrient intake and high reproductive rate, on one hand and slow ageing on the other.
- Team Members
Name Title Email Mumtaz Ahmad Media preparation technician mumtaz.ahmad@ucl.ac.uk Magda Atilano Post-doctoral researcher m.atilano@ucl.ac.uk Helen Fraser Clinical PhD student helen.fraser.14@ucl.ac.uk Matias Fuentealba PhD student matias.valenzuela.16@ucl.ac.uk Ashling Giblin PhD student ashling.giblin.19@ucl.ac.uk Enric Ureña Post-doctoral researcher e.sala@ucl.ac.uk Nathan Woodling Alzheimer's Society Research Fellow n.woodling@ucl.ac.uk Bowen Xu PhD Student bowen.xu.18@ucl.ac.uk